DrugDomain v2.0
coming soon
DrugDomain database reports:
1. ECOD domains of proteins that are targets for small molecules and drugs
2. Small molecule binding-associated post-translational modifications (PTMs)(example)
References:
1. Kirill E. Medvedev, R. Dustin Schaeffer, Nick V. Grishin (2024) DrugDomain: The evolutionary context of drugs and small molecules bound to domains. Protein Science 33(8): e5116 PMID: 38979784
2. Kirill E. Medvedev, R. Dustin Schaeffer, Nick V. Grishin (2025) Leveraging AI to Explore Structural Contexts of Post-Translational Modifications in Drug Binding. Journal of Chemoinformatics 17(1): 67 PMID: 40320551