Ligand name: Cobimetinib
PDB ligand accession: EUI
DrugBank: DB05239
PubChem: 16222096
ChEMBL: CHEMBL2146883
InChI Key: BSMCAPRUBJMWDF-KRWDZBQOSA-N
SMILES: OC1(CN(C1)C(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)[C@@H]1CCCCN1
Drug action: n/a

List of small molecule binding-associated PTMs for Q02750

Residue	UniProt number	Type of PTM	AlphaFold3 models	Rosetta models	Chai-1 models
SER	194	Phosphorylation		PyMOL_RFAA
SER	212	Phosphorylation		PyMOL_RFAA
THR	226	Phosphorylation		PyMOL_RFAA
SER	228	Phosphorylation		PyMOL_RFAA
TYR	229	Phosphorylation			PyMOL_Chai1
LYS	192	Ubiquitination
LYS	205	Ubiquitination
SER	218	Phosphorylation		PyMOL_RFAA
SER	222	Phosphorylation		PyMOL_RFAA
LYS	57	Ubiquitination