Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: CHOLINE ION
PDB ligand accession: CHT
DrugBank: DB00122
PubChem: 305
ChEMBL: CHEMBL920
InChI Key: OEYIOHPDSNJKLS-UHFFFAOYSA-N
SMILES: C[N+](C)(C)CCO

ClassyFire chemical classification:

List of proteins that are targets for DB00122

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P54582_CHT P54582 Glycine betaine transporter n/a
2 P06653_CHT P06653 Autolysin (EC 3.5.1.28) n/a
3 P49585_CHT P49585 Choline-phosphate cytidylyltransferase A product of
4 P02714_CHT P02714 Acetylcholine receptor subunit n/a
5 D0VWT1_CHT D0VWT1 Choline kinase n/a
6 P59206_CHT P59206 Putative endo-beta-N-acetylglucosaminidase (EC n/a
7 Q8IEE9_CHT Q8IEE9 choline-phosphate cytidylyltransferase (EC n/a
8 P17202_CHT P17202 Aminoaldehyde dehydrogenase BADH n/a
9 O69787_CHT O69787 Choline-sulfatase (EC 3.1.6.6) n/a
10 P02718_CHT P02718 Acetylcholine receptor subunit n/a
11 P15057_CHT P15057 Lysozyme (EC 3.2.1.17) n/a
12 Q8DR52_CHT Q8DR52 Choline-binding protein F n/a
13 A0A410NSD4_CHT A0A410NSD4 Choline-sulfatase (EC 3.1.6.6) n/a
14 Q93MI3_CHT Q93MI3 Choline kinase (Phosphotransferase) n/a
15 Q30W70_CHT Q30W70 Choline trimethylamine-lyase (Choline n/a
16 P28329_CHT P28329 Choline O-acetyltransferase (CHOACTase) n/a
17 O14939_CHT O14939 Phospholipase D2 (PLD product of
18 C7MT25_CHT C7MT25 Transcriptional regulator n/a
19 P21836_CHT P21836 Acetylcholinesterase (AChE) (EC n/a
20 A0A0E7XN74_CHT A0A0E7XN74 Drug/metabolite transporter (DMT) n/a
21 P31522_CHT P31522 pH 6 antigen n/a
22 O32243_CHT O32243 Glycine betaine/carnitine/choline-binding protein n/a
23 P45723_CHT P45723 1-phosphatidylinositol phosphodiesterase (EC n/a
24 P31016_CHT P31016 Disks large homolog n/a
25 A0A0M3KL44_CHT A0A0M3KL44 Choline trimethylamine-lyase (Choline n/a
26 P36544_CHT P36544 Neuronal acetylcholine receptor n/a
27 Q9HVF8_CHT Q9HVF8 Probable chemotaxis transducer n/a
28 A0A0H2UNH0_CHT A0A0H2UNH0 Choline binding protein n/a
29 P22303_CHT P22303 Acetylcholinesterase (AChE) (EC product of IC50(nM) = 3013006.02
30 J1UPV3_CHT J1UPV3 deleted n/a
31 Q8TZI9_CHT Q8TZI9 Glycerophosphodiester phosphodiesterase n/a
32 Q13393_CHT Q13393 Phospholipase D1 (PLD product of
33 P06276_CHT P06276 Cholinesterase (EC 3.1.1.8) product of
34 Q9Y5K3_CHT Q9Y5K3 Choline-phosphate cytidylyltransferase B product of
35 P00698_CHT P00698 Lysozyme C (EC n/a
36 Q9Z4J8_CHT Q9Z4J8 1,4-beta-N-acetylmuramidase (EC 3.2.1.17, n/a
37 Q9UBC3_CHT Q9UBC3 DNA (cytosine-5)-methyltransferase 3B n/a
38 P02710_CHT P02710 Acetylcholine receptor subunit n/a
39 Q8TCT1_CHT Q8TCT1 Phosphoethanolamine/phosphocholine phosphatase (EC product of
40 Q92N37_CHT Q92N37 Choline ABC transporter, n/a
41 A0A3B6UEU3_CHT A0A3B6UEU3 (3R)-3-[(carboxymethyl)amino]fatty acid oxygenase/decarboxylase n/a
42 P43005_CHT P43005 Excitatory amino acid n/a
43 Q45462_CHT Q45462 Choline-binding protein n/a
44 Q97RW9_CHT Q97RW9 deleted n/a