Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: LYSINE
PDB ligand accession: LYS
DrugBank: DB00123
PubChem: 641599;5460926;24848423;162317967;
ChEMBL: n/a
InChI Key: KDXKERNSBIXSRK-YFKPBYRVSA-O
SMILES: C(CC[NH3+])CC(C(=O)O)N

ClassyFire chemical classification:

List of proteins that are targets for DB00123

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q5CR27_LYS Q5CR27 Lysine--tRNA ligase (EC n/a
2 W6JQJ6_LYS W6JQJ6 Tryptophan 2-monooxygenase (EC n/a
3 P50033_LYS P50033 C-phycocyanin beta subunit n/a
4 O59188_LYS O59188 HTH-type transcriptional regulator n/a
5 P74569_LYS P74569 Aspartokinase (EC 2.7.2.4) n/a
6 Q58497_LYS Q58497 Diaminopimelate decarboxylase (DAP n/a
7 P50032_LYS P50032 C-phycocyanin alpha subunit n/a
8 A0A0G4DCU0_LYS A0A0G4DCU0 L-Lysine alpha-oxidase n/a
9 G8XHD5_LYS G8XHD5 L-lysine 4-chlorinase (EC n/a
10 A0A7Y0ZV07_LYS A0A7Y0ZV07 Ornithine cyclodeaminase family n/a
11 P9WFW3_LYS P9WFW3 Aspartate--tRNA(Asp/Asn) ligase (EC n/a
12 E1FQP0_LYS E1FQP0 deleted n/a
13 A0A066Q637_LYS A0A066Q637 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
14 Q9PPB4_LYS Q9PPB4 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
15 D1MH64_LYS D1MH64 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
16 A0A0J9X1X3_LYS A0A0J9X1X3 L-lysine oxidase (EC n/a
17 P00736_LYS P00736 Complement C1r subcomponent n/a
18 Q9LYU8_LYS Q9LYU8 Aspartokinase 1, chloroplastic n/a
19 A0A4Y5PW22_LYS A0A4Y5PW22 Allophycocyanin alpha n/a
20 P00861_LYS P00861 Diaminopimelate decarboxylase (DAP n/a
21 P0A8N3_LYS P0A8N3 Lysine--tRNA ligase (EC n/a
22 A0A2Z5X7B9_LYS A0A2Z5X7B9 Methyltransferase n/a
23 A0A4Y5PW23_LYS A0A4Y5PW23 Allophycocyanin beta n/a
24 P02911_LYS P02911 Lysine/arginine/ornithine-binding periplasmic protein n/a
25 B4XMC6_LYS B4XMC6 Diaminopimelate decarboxylase (DAP n/a
26 Q6P179_LYS Q6P179 Endoplasmic reticulum aminopeptidase n/a
27 P96896_LYS P96896 Leucine-responsive regulatory protein n/a
28 O87198_LYS O87198 Homocitrate synthase (HCS) n/a
29 G7CF12_LYS G7CF12 Lysine--tRNA ligase (EC n/a
30 Q6WVP6_LYS Q6WVP6 Arginase (EC 3.5.3.1) n/a
31 Q74NK7_LYS Q74NK7 Permuted papain-like amidase n/a
32 F2JXJ3_LYS F2JXJ3 L-lysine 6-oxidase (EC n/a
33 A0A085QWM0_LYS A0A085QWM0 Na(+)-translocating NADH-quinone reductase n/a
34 A0A8M0FGT0_LYS A0A8M0FGT0 Lysine hydroxylase n/a
35 D9UBW0_LYS D9UBW0 Lysine cyclodeaminase (EC n/a
36 P0A6L2_LYS P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
37 Q15046_LYS Q15046 Lysine--tRNA ligase (EC n/a
38 A5LD17_LYS A5LD17 deleted n/a
39 A0A085ST13_LYS A0A085ST13 Na(+)-translocating NADH-quinone reductase n/a
40 A0A655PZA5_LYS A0A655PZA5 Na(+)-translocating NADH-quinone reductase n/a
41 A0A1H0BKU7_LYS A0A1H0BKU7 ArpA protein n/a
42 Q72JG5_LYS Q72JG5 Amino acid ABC n/a
43 C3P9L8_LYS C3P9L8 deleted n/a
44 P00800_LYS P00800 Thermolysin (EC 3.4.24.27) n/a
45 C7QJ42_LYS C7QJ42 L-lysine 3-hydroxylase (EC n/a
46 P09890_LYS P09890 Diaminopimelate decarboxylase (DAP n/a
47 P15057_LYS P15057 Lysozyme (EC 3.2.1.17) n/a
48 A9DKW4_LYS A9DKW4 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
49 Q8W5Y8_LYS Q8W5Y8 Ply protein n/a
50 P31848_LYS P31848 Diaminopimelate decarboxylase (DAP n/a
51 P53634_LYS P53634 Dipeptidyl peptidase 1 n/a
52 Q43088_LYS Q43088 Ribulose-1,5 bisphosphate carboxylase/oxygenase n/a
53 P08660_LYS P08660 Lysine-sensitive aspartokinase 3 n/a
54 Q9UIQ6_LYS Q9UIQ6 Leucyl-cystinyl aminopeptidase (Cystinyl n/a
55 W7JP72_LYS W7JP72 Lysine--tRNA ligase (EC n/a
56 Q9WXM1_LYS Q9WXM1 L-Ala-D/L-Glu epimerase (AE n/a
57 P14825_LYS P14825 Lysine--tRNA ligase, heat n/a
58 P29148_LYS P29148 Bacillolysin (EC 3.4.24.28) n/a
59 Q9NTG7_LYS Q9NTG7 NAD-dependent protein deacetylase n/a
60 P24171_LYS P24171 Dipeptidyl carboxypeptidase (EC n/a
61 D7U7T8_LYS D7U7T8 4-hydroxy-tetrahydrodipicolinate synthase (EC n/a
62 Q9LZX6_LYS Q9LZX6 4-hydroxy-tetrahydrodipicolinate synthase 1, n/a
63 D0VWX8_LYS D0VWX8 ArtJ n/a
64 Q5SE95_LYS Q5SE95 L-ornithine N(5)-monooxygenase (OMO) n/a
65 Q7MAG0_LYS Q7MAG0 BINDING COMPONENT OF n/a
66 O42629_LYS O42629 Fructosyl amine:oxygen oxidoreductase n/a
67 P53608_LYS P53608 Arginase (EC 3.5.3.1) n/a
68 Q03164_LYS Q03164 Histone-lysine N-methyltransferase 2A n/a
69 P0A5Y6_LYS P0A5Y6 Enoyl-[acyl-carrier-protein] reductase [NADH] n/a
70 Q9FVC8_LYS Q9FVC8 4-hydroxy-tetrahydrodipicolinate synthase 2, n/a
71 A0A1S3TUX2_LYS A0A1S3TUX2 Uncharacterized protein LOC106759053 n/a
72 P0A8N5_LYS P0A8N5 Lysine--tRNA ligase, heat n/a
73 Q76353_LYS Q76353 Integrase n/a
74 Q94A94_LYS Q94A94 Diaminopimelate decarboxylase 2, n/a
75 Q5SI78_LYS Q5SI78 Arginase (EC 3.5.3.1) n/a
76 H1XW48_LYS H1XW48 MutT/NUDIX family protein n/a
77 A0A0H3FMF8_LYS A0A0H3FMF8 Cystathionine beta-lyase (EC n/a
78 B2FQ84_LYS B2FQ84 Lysine--tRNA ligase (EC n/a
79 A0A2K1KKM6_LYS A0A2K1KKM6 N-acetyltransferase domain-containing protein n/a
80 P35049_LYS P35049 Trypsin (EC 3.4.21.4) n/a
81 B0BAN6_LYS B0BAN6 Lysine--tRNA ligase (EC n/a
82 Q8PWY1_LYS Q8PWY1 Pyrrolysine--tRNA ligase (EC n/a
83 W7F9C1_LYS W7F9C1 Lysine--tRNA ligase (EC n/a
84 A0PV47_LYS A0PV47 Lysine--tRNA ligase (EC n/a
85 P05089_LYS P05089 Arginase-1 (EC 3.5.3.1) n/a
86 A0A0F4VK59_LYS A0A0F4VK59 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
87 Q6F3I7_LYS Q6F3I7 Dipeptidyl aminopeptidase 4 n/a
88 M1V4H9_LYS M1V4H9 4-hydroxy-tetrahydrodipicolinate synthase (EC n/a
89 P04825_LYS P04825 Aminopeptidase N (EC n/a
90 D8A942_LYS D8A942 deleted n/a
91 Q46E79_LYS Q46E79 3-methyl-D-ornithine--L-lysine ligase (EC n/a
92 Q9XBQ8_LYS Q9XBQ8 L-lysine 2,3-aminomutase (LAM) n/a
93 O67728_LYS O67728 tRNA(Ile)-lysidine synthase (EC n/a
94 J3BZS6_LYS J3BZS6 L-lysine 4-hydroxylase (EC n/a
95 Q5LTV6_LYS Q5LTV6 His/Glu/Gln/Arg/opine family ABC n/a
96 Q8VUS5_LYS Q8VUS5 [LysW]-lysine hydrolase (EC n/a
97 P43133_LYS P43133 Thermolysin (EC 3.4.24.27) n/a
98 P30419_LYS P30419 Glycylpeptide N-tetradecanoyltransferase 1 n/a
99 P26512_LYS P26512 Aspartokinase (EC 2.7.2.4) n/a
100 Q9Y823_LYS Q9Y823 Homocitrate synthase, mitochondrial n/a
101 Q8IDJ8_LYS Q8IDJ8 Lysine--tRNA ligase (EC n/a
102 Q8DQQ1_LYS Q8DQQ1 Peptidase M15B domain-containing n/a
103 B7M7I1_LYS B7M7I1 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
104 A0A5K6CNB8_LYS A0A5K6CNB8 Delta-poly-L-ornithine synthetase (Delta-POs) n/a
105 Q93C54_LYS Q93C54 aspartate kinase (EC n/a
106 P63509_LYS P63509 L-lysine-epsilon aminotransferase (L-lysine n/a
107 Q14498_LYS Q14498 RNA-binding protein 39 n/a
108 F0L8Z6_LYS F0L8Z6 deleted n/a
109 P06202_LYS P06202 Periplasmic oligopeptide-binding protein n/a
110 P12821_LYS P12821 Angiotensin-converting enzyme (ACE) n/a
111 N6FDB4_LYS N6FDB4 deleted n/a
112 O69077_LYS O69077 Aspartokinase (EC 2.7.2.4) n/a
113 Q2SXD6_LYS Q2SXD6 Lysine--tRNA ligase (EC n/a
114 A0A085RHY8_LYS A0A085RHY8 Na(+)-translocating NADH-quinone reductase n/a
115 Q949X7_LYS Q949X7 Diaminopimelate decarboxylase 1, n/a
116 P9WFU9_LYS P9WFU9 Lysine--tRNA ligase 1 n/a
117 Q97MC0_LYS Q97MC0 Aspartokinase (EC 2.7.2.4) n/a