Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: SERINE
PDB ligand accession: SER
DrugBank: DB00133
PubChem: 5951;6857581;
ChEMBL: CHEMBL11298
InChI Key: MTCFGRXMJLQNBG-REOHCLBHSA-N
SMILES: C(C(C(=O)O)N)O

ClassyFire chemical classification:

List of proteins that are targets for DB00133

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 O67323_SER O67323 Alanine--tRNA ligase (EC n/a
2 A0A0D6I3Y9_SER A0A0D6I3Y9 Serine acetyltransferase (EC n/a
3 A0A5K1VAP1_SER A0A5K1VAP1 Tryptophan synthase beta n/a
4 D8A942_SER D8A942 deleted n/a
5 Q9UZ14_SER Q9UZ14 Threonine--tRNA ligase (EC n/a
6 Q8GXJ4_SER Q8GXJ4 Glutamate receptor 3.4 n/a
7 Q7SIB6_SER Q7SIB6 Serine hydroxymethyltransferase (SHMT) n/a
8 P0DTD1_SER P0DTD1 Replicase polyprotein 1ab n/a
9 Q2MGH6_SER Q2MGH6 Endo-alpha-N-acetylgalactosaminidase (EC 3.2.1.97) n/a
10 A0A4V8GZY4_SER A0A4V8GZY4 BPa0997 n/a
11 Q8ZNT7_SER Q8ZNT7 D-cysteine desulfhydrase (EC n/a
12 L4EJM2_SER L4EJM2 deleted n/a
13 Q2F1K8_SER Q2F1K8 Agglutinin n/a
14 Q15465_SER Q15465 Sonic hedgehog protein n/a
15 P49591_SER P49591 Serine--tRNA ligase, cytoplasmic n/a
16 A0A085T373_SER A0A085T373 deleted n/a
17 A0A2I9DQ46_SER A0A2I9DQ46 Bifunctional cytochrome P450/NADPH--P450 n/a
18 K5BDL0_SER K5BDL0 Glucosylglycerate hydrolase (GG n/a
19 A0A0H2YN38_SER A0A0H2YN38 F5/8 type C n/a
20 Q89ZX7_SER Q89ZX7 Peptidase M60 domain-containing n/a
21 P0AGL2_SER P0AGL2 Putative reactive intermediate n/a
22 Q5SI56_SER Q5SI56 Serine hydroxymethyltransferase (SHMT) n/a
23 P00933_SER P00933 Tryptophan synthase beta n/a
24 P01724_SER P01724 Ig lambda-1 chain n/a
25 A0A0D6FWC1_SER A0A0D6FWC1 Tryptophan synthase alpha n/a
26 A0QJI1_SER A0QJI1 Phosphoserine phosphatase (PSP) n/a
27 B4ECY9_SER B4ECY9 Serine hydroxymethyltransferase (SHMT) n/a
28 A0PQG8_SER A0PQG8 Dihydrofolate reductase (EC n/a
29 Q5SI02_SER Q5SI02 L-glutamate gamma-semialdehyde dehydrogenase n/a
30 Q5F6X0_SER Q5F6X0 Serine acetyltransferase (EC n/a
31 Q46AN5_SER Q46AN5 Type-2 serine--tRNA ligase n/a
32 P03952_SER P03952 Plasma kallikrein (EC n/a
33 Q9BXC1_SER Q9BXC1 Probable G-protein coupled n/a
34 Q8RE94_SER Q8RE94 Cysteine synthase (EC n/a
35 P04825_SER P04825 Aminopeptidase N (EC n/a
36 G1SGR6_SER G1SGR6 Large ribosomal subunit n/a
37 G1SKF7_SER G1SKF7 Large ribosomal subunit n/a
38 P50383_SER P50383 Tryptophan synthase beta n/a
39 P0A9T0_SER P0A9T0 D-3-phosphoglycerate dehydrogenase (PGDH) n/a
40 P31013_SER P31013 Tyrosine phenol-lyase (EC n/a
41 Q3D9X5_SER Q3D9X5 deleted n/a
42 P03372_SER P03372 Estrogen receptor (ER) n/a
43 G1SKZ8_SER G1SKZ8 Large ribosomal subunit n/a
44 O60844_SER O60844 Zymogen granule membrane n/a
45 P52011_SER P52011 Peptidyl-prolyl cis-trans isomerase n/a
46 P78330_SER P78330 Phosphoserine phosphatase (PSP) n/a
47 P9WNY5_SER P9WNY5 Probable 3-hydroxyisobutyrate dehydrogenase n/a
48 Q93AT8_SER Q93AT8 AcsD n/a
49 O59010_SER O59010 Glutamate transporter homolog n/a
50 P73797_SER P73797 Slr1257 protein n/a
51 P0A544_SER P0A544 D-3-phosphoglycerate dehydrogenase (PGDH) n/a
52 O58307_SER O58307 Alanyl-tRNA editing protein n/a
53 P0A8M3_SER P0A8M3 Threonine--tRNA ligase (EC n/a
54 G1SE28_SER G1SE28 Large ribosomal subunit n/a
55 P53634_SER P53634 Dipeptidyl peptidase 1 n/a
56 A0A4V8GZY3_SER A0A4V8GZY3 BPa0997 n/a
57 P30419_SER P30419 Glycylpeptide N-tetradecanoyltransferase 1 n/a
58 O31562_SER O31562 Putative metal-dependent hydrolase n/a
59 A0A0R4I973_SER A0A0R4I973 ML032222a iGluR n/a
60 A5K8L9_SER A5K8L9 glycine hydroxymethyltransferase (EC n/a
61 P33183_SER P33183 Nigrin b (Agglutinin n/a
62 P0A2K1_SER P0A2K1 Tryptophan synthase beta n/a
63 Q834W6_SER Q834W6 Hydrophobic dipeptide epimerase n/a
64 Q9I5W4_SER Q9I5W4 Immunomodulating metalloprotease (EC n/a
65 Q8YYB7_SER Q8YYB7 Type II site-specific n/a
66 A0A1G4HYZ0_SER A0A1G4HYZ0 Uncharacterized protein n/a
67 P81371_SER P81371 Seed lectin (VML) n/a
68 Q00022_SER Q00022 Agaricus bisporus lectin n/a
69 Q3K7T6_SER Q3K7T6 Putative methyl-accepting chemotaxis n/a
70 Q5H4T8_SER Q5H4T8 Cystathionine gamma-lyase-like protein n/a
71 Q94C74_SER Q94C74 Serine hydroxymethyltransferase 2, n/a
72 A1E280_SER A1E280 Tryptophan 6-halogenase ThaL n/a
73 O59791_SER O59791 Serine racemase (EC n/a
74 P12821_SER P12821 Angiotensin-converting enzyme (ACE) n/a
75 Q9ZVL6_SER Q9ZVL6 UPF0603 protein At1g54780, n/a
76 A0A4Y8GT61_SER A0A4Y8GT61 Aspartate 1-decarboxylase (EC n/a
77 Q9H5I1_SER Q9H5I1 Histone-lysine N-methyltransferase SUV39H2 n/a
78 A0A0T9NP28_SER A0A0T9NP28 deleted n/a
79 F8UNJ8_SER F8UNJ8 F5/8 type C n/a
80 D6PBM7_SER D6PBM7 NAD dependent epimerase/dehydratase n/a
81 P14618_SER P14618 Pyruvate kinase PKM n/a EC50(nM) = 1300000.0
82 A0A0H3FMF8_SER A0A0H3FMF8 Cystathionine beta-lyase (EC n/a
83 D4S0D1_SER D4S0D1 3-dehydroquinate dehydratase (3-dehydroquinase) n/a
84 G8UQY8_SER G8UQY8 Serpin n/a
85 P02942_SER P02942 Methyl-accepting chemotaxis protein n/a
86 A0A2K6VKP7_SER A0A2K6VKP7 proline--tRNA ligase (EC n/a
87 O24313_SER O24313 Basic agglutinin (WBA n/a
88 A0A0H3KGN3_SER A0A0H3KGN3 Trehalose-6-phosphate synthase (EC n/a
89 R4GRU5_SER R4GRU5 BEL-beta trefoil n/a
90 P21742_SER P21742 Beta-hordothionin n/a
91 A0A2Z3TXF1_SER A0A2Z3TXF1 deleted n/a
92 P11838_SER P11838 Endothiapepsin (EC 3.4.23.22) n/a
93 Q8A921_SER Q8A921 Beta-galactosidase n/a
94 Q833V2_SER Q833V2 Glycosyl hydrolase, family n/a
95 P57772_SER P57772 Selenocysteine-specific elongation factor n/a
96 A7BFV6_SER A7BFV6 Serine palmitoyltransferase (SPT) n/a
97 Q8IUN9_SER Q8IUN9 C-type lectin domain n/a
98 A0A5C1IY53_SER A0A5C1IY53 Unusual AA9 family n/a
99 Q96T21_SER Q96T21 Selenocysteine insertion sequence-binding n/a
100 Q9UPC5_SER Q9UPC5 Probable G-protein coupled n/a
101 Q9U1M8_SER Q9U1M8 Myosin-I heavy chain n/a
102 A0A0H6VSA0_SER A0A0H6VSA0 deleted n/a
103 Q9U8X2_SER Q9U8X2 serine O-acetyltransferase (EC n/a
104 P05092_SER P05092 Peptidyl-prolyl cis-trans isomerase n/a
105 Q57WF8_SER Q57WF8 Peptidyl-prolyl cis-trans isomerase n/a
106 P56625_SER P56625 Lectin B4 (VVLB4) n/a
107 E9P5T5_SER E9P5T5 Glutamate receptor 1 n/a
108 P00929_SER P00929 Tryptophan synthase alpha n/a
109 I1KHY6_SER I1KHY6 serine O-acetyltransferase (EC n/a
110 Q5ZX43_SER Q5ZX43 Cystathionine beta-lyase (EC n/a