Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: TYROSINE
PDB ligand accession: TYR
DrugBank: DB00135
PubChem: 6057;6942100;
ChEMBL: CHEMBL925
InChI Key: OUYCCCASQSFEME-QMMMGPOBSA-N
SMILES: c1cc(ccc1CC(C(=O)O)N)O

ClassyFire chemical classification:

List of proteins that are targets for DB00135

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P01175_TYR P01175 Oxytocin-neurophysin 1 (OT-NPI) n/a
2 A0A0H2ZBG1_TYR A0A0H2ZBG1 PvdP n/a
3 Q8A3I4_TYR Q8A3I4 Alpha-L-fucosidase n/a
4 P27002_TYR P27002 Phenylalanine--tRNA ligase beta n/a
5 O67636_TYR O67636 Prephenate dehydrogenase n/a
6 B4FNK8_TYR B4FNK8 Chorismate mutase 1, n/a
7 P00509_TYR P00509 Aspartate aminotransferase (AspAT) n/a
8 S0EH60_TYR S0EH60 Dimethylallyltryptophan synthase 1 n/a
9 P00888_TYR P00888 Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive n/a
10 D9QA55_TYR D9QA55 Arginine repressor n/a
11 P96896_TYR P96896 Leucine-responsive regulatory protein n/a
12 E1BQ43_TYR E1BQ43 deleted n/a
13 P00730_TYR P00730 Carboxypeptidase A1 (EC n/a
14 B4RP13_TYR B4RP13 Tyrosine--tRNA ligase (EC n/a
15 Q57834_TYR Q57834 Tyrosine--tRNA ligase (EC n/a
16 Q8GMG0_TYR Q8GMG0 MIO-dependent tyrosine 2,3-aminomutase n/a
17 P03372_TYR P03372 Estrogen receptor (ER) n/a
18 A0A0E3UAP8_TYR A0A0E3UAP8 deleted n/a
19 A0A4Y7X244_TYR A0A4Y7X244 Na+-dependent transporter (Sodium-dependent n/a
20 Q81P63_TYR Q81P63 Prephenate dehydrogenase (EC n/a
21 P12063_TYR P12063 Tyrosine--tRNA ligase, mitochondrial n/a
22 A0A086HYS2_TYR A0A086HYS2 Tyrosine--tRNA ligase (EC n/a
23 Q7IIB7_TYR Q7IIB7 NADH-ubiquinone oxidoreductase chain n/a
24 Q16769_TYR Q16769 Glutaminyl-peptide cyclotransferase (EC n/a
25 Q9HXC7_TYR Q9HXC7 Dual specificity protein n/a
26 O58739_TYR O58739 Tyrosine--tRNA ligase (EC n/a
27 A1HPQ5_TYR A1HPQ5 Thiazole biosynthesis protein n/a
28 G0WVH3_TYR G0WVH3 ApnAA1 n/a
29 B4SLK2_TYR B4SLK2 Dipeptidyl-peptidase (EC 3.4.14.-) n/a
30 Q71K68_TYR Q71K68 NADH-ubiquinone oxidoreductase chain n/a
31 Q9RVZ5_TYR Q9RVZ5 Aminopeptidase N (EC n/a
32 Q7KZF4_TYR Q7KZF4 Staphylococcal nuclease domain-containing n/a
33 P81947_TYR P81947 Tubulin alpha-1B chain n/a
34 Q9K169_TYR Q9K169 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
35 C5P455_TYR C5P455 Tyrosine--tRNA ligase (EC n/a
36 Q92MG1_TYR Q92MG1 Cyclohexadienyl dehydrogenase and n/a
37 P27001_TYR P27001 Phenylalanine--tRNA ligase alpha n/a
38 V5YM14_TYR V5YM14 Dipeptidyl aminopeptidase BII n/a
39 P00951_TYR P00951 Tyrosine--tRNA ligase (EC n/a
40 P01180_TYR P01180 Vasopressin-neurophysin 2-copeptin (AVP-NPII) n/a
41 P17643_TYR P17643 5,6-dihydroxyindole-2-carboxylic acid oxidase n/a
42 P00777_TYR P00777 Streptogrisin-B (EC 3.4.21.81) n/a
43 Q6B856_TYR Q6B856 Tubulin beta-2B chain n/a
44 Q9WYH8_TYR Q9WYH8 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
45 P54577_TYR P54577 Tyrosine--tRNA ligase, cytoplasmic n/a
46 P15369_TYR P15369 Scytalidopepsin B (SLB) n/a
47 Q9I000_TYR Q9I000 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
48 O29524_TYR O29524 Ribosomal RNA small n/a
49 O29482_TYR O29482 Tyrosine--tRNA ligase (EC n/a
50 P04958_TYR P04958 Tetanus toxin (EC n/a
51 Q18A65_TYR Q18A65 ABC-type transport system, n/a
52 Q8IAR7_TYR Q8IAR7 tyrosine--tRNA ligase (EC n/a
53 P00952_TYR P00952 Tyrosine--tRNA ligase (EC n/a
54 A0A164UM01_TYR A0A164UM01 deleted n/a
55 P42738_TYR P42738 Chorismate mutase 1, n/a
56 U6N9P2_TYR U6N9P2 deleted n/a
57 A0A2H0ZNV2_TYR A0A2H0ZNV2 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
58 O82415_TYR O82415 Tyrosine decarboxylase (PsTyDC) n/a
59 P00800_TYR P00800 Thermolysin (EC 3.4.24.27) n/a
60 O53512_TYR O53512 Phospho-2-dehydro-3-deoxyheptonate aldolase AroG n/a
61 P43902_TYR P43902 T-protein [Includes: Chorismate n/a
62 A0A1S9DK56_TYR A0A1S9DK56 tyrosinase (EC 1.14.18.1) n/a
63 Q5BCM1_TYR Q5BCM1 Tyrosine--tRNA ligase (EC n/a
64 B2ZB02_TYR B2ZB02 Tyrosinase n/a
65 Q834W6_TYR Q834W6 Hydrophobic dipeptide epimerase n/a
66 B9K712_TYR B9K712 Iodotyrosine deiodinase (EC n/a
67 I1MYY4_TYR I1MYY4 Prephenate dehydrogenase 1 n/a
68 A0A4X1VYV0_TYR A0A4X1VYV0 deleted n/a
69 P32178_TYR P32178 Chorismate mutase (CM) n/a
70 P04825_TYR P04825 Aminopeptidase N (EC n/a
71 P53634_TYR P53634 Dipeptidyl peptidase 1 n/a
72 P27348_TYR P27348 14-3-3 protein theta n/a
73 A0A0J9X1X3_TYR A0A0J9X1X3 L-lysine oxidase (EC n/a