Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: GLYCINE
PDB ligand accession: GLY
DrugBank: DB00145
PubChem: 750;5257127;
ChEMBL: CHEMBL773
InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES: C(C(=O)O)N

ClassyFire chemical classification:

List of proteins that are targets for DB00145

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P39900_GLY P39900 Macrophage metalloelastase (MME) n/a
2 P0DTC1_GLY P0DTC1 Replicase polyprotein 1a n/a
3 P00477_GLY P00477 Serine hydroxymethyltransferase (SHMT) n/a
4 Q00960_GLY Q00960 Glutamate receptor ionotropic, n/a EC50(nM) = 240.0
5 O66905_GLY O66905 Glycerol-3-phosphate acyltransferase (Acyl-PO4 n/a
6 A0A0T9NP28_GLY A0A0T9NP28 deleted n/a
7 Q8WSF8_GLY Q8WSF8 Soluble acetylcholine receptor n/a
8 Q95HB9_GLY Q95HB9 HLA class II n/a
9 P24171_GLY P24171 Dipeptidyl carboxypeptidase (EC n/a
10 Q9RC92_GLY Q9RC92 Unsaturated glucuronyl hydrolase n/a
11 Q93LE9_GLY Q93LE9 Peptide deformylase (PDF) n/a
12 Q04771_GLY Q04771 Activin receptor type-1 n/a
13 Q6GTX8_GLY Q6GTX8 Leukocyte-associated immunoglobulin-like receptor n/a
14 A7Y7W1_GLY A7Y7W1 Periplasmic dipeptide-binding protein n/a
15 P52011_GLY P52011 Peptidyl-prolyl cis-trans isomerase n/a
16 O15460_GLY O15460 Prolyl 4-hydroxylase subunit n/a
17 Q00959_GLY Q00959 Glutamate receptor ionotropic, n/a EC50(nM) = 990.0
18 Q6DC22_GLY Q6DC22 Glycine receptor beta n/a
19 A0A0S4TLR1_GLY A0A0S4TLR1 Fucose-binding lectin protein n/a
20 O93430_GLY O93430 Glycine receptor subunit n/a
21 Q1LBR9_GLY Q1LBR9 Phthalate 4,5-dioxygenase, subunit n/a
22 J9VYP5_GLY J9VYP5 Bifunctional purine biosynthetic n/a
23 C0KD18_GLY C0KD18 Glutamate receptor ionotropic, n/a
24 Q9XAL8_GLY Q9XAL8 Copper oxidase n/a
25 Q9Y657_GLY Q9Y657 Spindlin-1 (Ovarian cancer-related n/a
26 Q5HE87_GLY Q5HE87 Serine hydroxymethyltransferase (SHMT) n/a
27 P48167_GLY P48167 Glycine receptor subunit ligand
28 P12955_GLY P12955 Xaa-Pro dipeptidase (X-Pro n/a
29 P23415_GLY P23415 Glycine receptor subunit ligand EC50(nM) = 95499.0
30 P0AEX9_GLY P0AEX9 Maltose/maltodextrin-binding periplasmic protein n/a
31 K5BDL0_GLY K5BDL0 Glucosylglycerate hydrolase (GG n/a
32 A0A072ZNL3_GLY A0A072ZNL3 Antibiotic biosynthesis monooxygenase n/a
33 Q9YBQ2_GLY Q9YBQ2 Acylamino-acid-releasing enzyme (AARE) n/a
34 P74102_GLY P74102 Orange carotenoid-binding protein n/a
35 D4L313_GLY D4L313 RNA-directed DNA polymerase n/a
36 A0A390C306_GLY A0A390C306 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC n/a
37 P53634_GLY P53634 Dipeptidyl peptidase 1 n/a
38 Q9NRK6_GLY Q9NRK6 ATP-binding cassette sub-family n/a
39 P20789_GLY P20789 Neurotensin receptor type n/a
40 Q185X7_GLY Q185X7 Beta-phosphoglucomutase (EC 5.4.2.6) n/a
41 B7H2D0_GLY B7H2D0 deleted n/a
42 Q6ITT5_GLY Q6ITT5 Chromosome partition protein n/a
43 A0A1H0BKU7_GLY A0A1H0BKU7 ArpA protein n/a
44 P01391_GLY P01391 Alpha-cobratoxin (Alpha-CT) (Alpha-CbT) n/a
45 Q9ZHG9_GLY Q9ZHG9 L-cysteine/cystine lyase C-DES n/a
46 A0A239KXH0_GLY A0A239KXH0 deleted n/a
47 Q5WPU5_GLY Q5WPU5 Genome polyprotein [Cleaved n/a
48 Q5EPH2_GLY Q5EPH2 Carboxypeptidase inhibitor (TCI) n/a
49 Q24995_GLY Q24995 Arylphorin (Lhp76) n/a
50 Q5L2C2_GLY Q5L2C2 Glycine oxidase (GO) n/a
51 P23687_GLY P23687 Prolyl endopeptidase (PE) n/a
52 P34896_GLY P34896 Serine hydroxymethyltransferase, cytosolic product of
53 A7Y407_GLY A7Y407 Beta-lactamase (EC 3.5.2.6) n/a
54 Q8VHN2_GLY Q8VHN2 Glutamate receptor ionotropic, n/a
55 Q47898_GLY Q47898 N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) n/a
56 F1RQB7_GLY F1RQB7 Glycine receptor alpha n/a
57 P81947_GLY P81947 Tubulin alpha-1B chain n/a
58 P15145_GLY P15145 Aminopeptidase N (AP-N) n/a
59 Q6RYW5_GLY Q6RYW5 Outer membrane protein n/a
60 P35439_GLY P35439 Glutamate receptor ionotropic, n/a IC50(nM) = 250.0
61 O15399_GLY O15399 Glutamate receptor ionotropic, n/a
62 P01009_GLY P01009 Alpha-1-antitrypsin (Alpha-1 protease n/a
63 P56410_GLY P56410 Ovotransferrin n/a
64 A0A4Y5PW22_GLY A0A4Y5PW22 Allophycocyanin alpha n/a
65 Q9F3C7_GLY Q9F3C7 Formylglycine-generating enzyme (FGE) n/a
66 Q9PPK3_GLY Q9PPK3 Glycine--tRNA ligase alpha n/a
67 Q96IY4_GLY Q96IY4 Carboxypeptidase B2 (EC n/a
68 A0A8I3B064_GLY A0A8I3B064 5,10-methenyltetrahydromethanopterin hydrogenase (EC n/a
69 Q9RQ20_GLY Q9RQ20 LysR family transcriptional n/a
70 A1E280_GLY A1E280 Tryptophan 6-halogenase ThaL n/a
71 Q6ZXC0_GLY Q6ZXC0 Metallocarboxypeptidase (EC 3.4.17.19) n/a
72 B1VBB0_GLY B1VBB0 chitinase (EC 3.2.1.14) n/a
73 P43616_GLY P43616 Cys-Gly metallodipeptidase DUG1 n/a
74 P31522_GLY P31522 pH 6 antigen n/a
75 Q9SJQ9_GLY Q9SJQ9 Fructose-bisphosphate aldolase 6, n/a
76 Q8N4I3_GLY Q8N4I3 Calcium/calmodulin-dependent protein kinase n/a
77 P00523_GLY P00523 Proto-oncogene tyrosine-protein kinase n/a
78 Q96W94_GLY Q96W94 Beta-alanine synthase (EC n/a
79 Q00961_GLY Q00961 Glutamate receptor ionotropic, n/a EC50(nM) = 210.0
80 Q9U1M8_GLY Q9U1M8 Myosin-I heavy chain n/a
81 Q12879_GLY Q12879 Glutamate receptor ionotropic, antagonist
82 P07511_GLY P07511 Serine hydroxymethyltransferase, cytosolic n/a
83 P54965_GLY P54965 Bile salt hydrolase/transferase n/a
84 Q2T9S0_GLY Q2T9S0 Tubulin beta-3 chain n/a
85 P01116_GLY P01116 GTPase KRas (EC n/a
86 P12821_GLY P12821 Angiotensin-converting enzyme (ACE) n/a
87 P18187_GLY P18187 Periplasmic [NiFe] hydrogenase n/a
88 Q99XG5_GLY Q99XG5 DNA gyrase subunit n/a
89 P71814_GLY P71814 Possible two component n/a
90 H6S0J1_GLY H6S0J1 Glutamate receptor kainate-like n/a
91 H6A2X0_GLY H6A2X0 Histo-blood group ABO n/a
92 P50033_GLY P50033 C-phycocyanin beta subunit n/a
93 A0A0H6VSA0_GLY A0A0H6VSA0 deleted n/a
94 Q82FC3_GLY Q82FC3 Secreted protein n/a
95 Q6DRA1_GLY Q6DRA1 Beta-lactamase (EC 3.5.2.6) n/a
96 P66937_GLY P66937 DNA gyrase subunit n/a
97 P56965_GLY P56965 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 n/a
98 Q5W271_GLY Q5W271 L-prolyl-[peptidyl-carrier protein] dehydrogenase n/a
99 A0A173M094_GLY A0A173M094 Taste receptor type n/a
100 P62937_GLY P62937 Peptidyl-prolyl cis-trans isomerase n/a
101 P15309_GLY P15309 Prostatic acid phosphatase n/a
102 G2Q1N4_GLY G2Q1N4 GH30 family xylanase n/a
103 A0A5C1IY53_GLY A0A5C1IY53 Unusual AA9 family n/a
104 F6IQS1_GLY F6IQS1 MHC class I n/a
105 Q9SUQ8_GLY Q9SUQ8 Dirigent protein 6 n/a
106 B4ECY9_GLY B4ECY9 Serine hydroxymethyltransferase (SHMT) n/a
107 A0A0R4I973_GLY A0A0R4I973 ML032222a iGluR n/a
108 P03992_GLY P03992 HLA class II n/a
109 P22966_GLY P22966 Angiotensin-converting enzyme (ACE) n/a
110 P18188_GLY P18188 Periplasmic [NiFe] hydrogenase n/a
111 P23416_GLY P23416 Glycine receptor subunit ligand
112 Q03154_GLY Q03154 Aminoacylase-1 (ACY-1) (EC n/a
113 Q8ZPA3_GLY Q8ZPA3 ABC transporter D-alanine-binding n/a
114 Q5ZXB6_GLY Q5ZXB6 Isocitrate dehydrogenase [NADP] n/a
115 P40051_GLY P40051 Intermediate cleaving peptidase n/a
116 A0A0H3FMF8_GLY A0A0H3FMF8 Cystathionine beta-lyase (EC n/a
117 P60293_GLY P60293 Chromosome partition protein n/a
118 Q7WYA8_GLY Q7WYA8 Metallo-beta-lactamase type 2 n/a
119 Q84KR7_GLY Q84KR7 phosphoenolpyruvate carboxylase (EC n/a
120 Q6KBX4_GLY Q6KBX4 Glycine receptor beta n/a
121 Q5H7I4_GLY Q5H7I4 Non-structural protein 1 n/a
122 O15305_GLY O15305 Phosphomannomutase 2 (PMM n/a
123 A0A173M0G2_GLY A0A173M0G2 Taste receptor, type n/a
124 B1ZMF4_GLY B1ZMF4 Putative acetyl xylan n/a
125 P41250_GLY P41250 Glycine--tRNA ligase (EC substrate
126 A8MI53_GLY A8MI53 Peptide methionine sulfoxide n/a
127 P01901_GLY P01901 H-2 class I n/a
128 P50440_GLY P50440 Glycine amidinotransferase, mitochondrial substrate
129 P01907_GLY P01907 HLA class II n/a
130 Q84AR1_GLY Q84AR1 L-methionine gamma-lyase (EC n/a
131 A0A1S5NV50_GLY A0A1S5NV50 Endolysin n/a
132 G3V9C5_GLY G3V9C5 Glutamate receptor n/a
133 A0A0A0G552_GLY A0A0A0G552 deleted n/a
134 O67323_GLY O67323 Alanine--tRNA ligase (EC n/a
135 U3KRF2_GLY U3KRF2 3-dehydroquinate synthase, chloroplastic n/a
136 B9A5C1_GLY B9A5C1 Protease (EC 3.4.22.39) n/a
137 Q5A5E0_GLY Q5A5E0 Dihydrofolate reductase (EC n/a
138 A9IWP7_GLY A9IWP7 protein adenylyltransferase (EC n/a
139 Q2LKZ0_GLY Q2LKZ0 Genome polyprotein [Cleaved n/a
140 Q5SI02_GLY Q5SI02 L-glutamate gamma-semialdehyde dehydrogenase n/a
141 B3KX63_GLY B3KX63 Crossover junction endonuclease n/a
142 Q1JU94_GLY Q1JU94 S-layer protein n/a
143 P11838_GLY P11838 Endothiapepsin (EC 3.4.23.22) n/a
144 P50032_GLY P50032 C-phycocyanin alpha subunit n/a
145 P22906_GLY P22906 Dihydrofolate reductase (EC n/a
146 O67854_GLY O67854 Na(+):neurotransmitter symporter (Snf n/a
147 P00730_GLY P00730 Carboxypeptidase A1 (EC n/a
148 Q81HW2_GLY Q81HW2 Potassium channel protein n/a
149 P01900_GLY P01900 H-2 class I n/a
150 P23847_GLY P23847 Dipeptide-binding protein (DBP) n/a
151 Q9R1M7_GLY Q9R1M7 Glutamate receptor ionotropic, n/a
152 N1P8Q8_GLY N1P8Q8 Nta1p n/a
153 A0A2K6VKP7_GLY A0A2K6VKP7 proline--tRNA ligase (EC n/a
154 P16621_GLY P16621 Tyrosine-protein phosphatase Lar n/a
155 U3BPN5_GLY U3BPN5 2-amino-3-ketobutyrate coenzyme A n/a
156 Q97SP8_GLY Q97SP8 deleted n/a
157 O00560_GLY O00560 Syntenin-1 (Melanoma differentiation-associated n/a
158 A7XY94_GLY A7XY94 Glutamate receptor ionotropic, n/a
159 Q7SIB6_GLY Q7SIB6 Serine hydroxymethyltransferase (SHMT) n/a
160 P30419_GLY P30419 Glycylpeptide N-tetradecanoyltransferase 1 n/a
161 Q7L266_GLY Q7L266 Isoaspartyl peptidase/L-asparaginase (EC n/a
162 Q1JGN6_GLY Q1JGN6 deleted n/a
163 A0A083ZKV5_GLY A0A083ZKV5 deleted n/a
164 Q9C8E7_GLY Q9C8E7 Glutamate receptor 3.3 n/a
165 Q10MW4_GLY Q10MW4 Basic helix-loop-helix, putative, n/a
166 P26012_GLY P26012 Integrin beta-8 n/a
167 A0A4Y5PW23_GLY A0A4Y5PW23 Allophycocyanin beta n/a
168 A8QIF8_GLY A8QIF8 Beta-lactamase (EC 3.5.2.6) n/a
169 Q93YT1_GLY Q93YT1 Glutamate receptor 3.2 n/a
170 P09331_GLY P09331 Exfoliative toxin A n/a
171 Q8K3A2_GLY Q8K3A2 tRNA 2'-phosphotransferase 1 n/a
172 Q9FEW9_GLY Q9FEW9 12-oxophytodienoate reductase 3 n/a
173 A0A2H4PPJ8_GLY A0A2H4PPJ8 Beta-lactamase (EC 3.5.2.6) n/a
174 A0A0H3JTG5_GLY A0A0H3JTG5 Lipoprotein n/a
175 Q8IEW2_GLY Q8IEW2 Peroxisomal membrane protein n/a
176 O75311_GLY O75311 Glycine receptor subunit ligand
177 A0A161XU12_GLY A0A161XU12 Uncharacterized protein n/a
178 C6F3U5_GLY C6F3U5 Ferulic acid decarboxylase n/a
179 P05092_GLY P05092 Peptidyl-prolyl cis-trans isomerase n/a
180 Q7BJX9_GLY Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC n/a
181 P06279_GLY P06279 Alpha-amylase (EC 3.2.1.1) n/a
182 P06756_GLY P06756 Integrin alpha-V (Vitronectin n/a
183 Q05586_GLY Q05586 Glutamate receptor ionotropic, n/a
184 P21524_GLY P21524 Ribonucleoside-diphosphate reductase large n/a
185 A7IZR5_GLY A7IZR5 Cry51Aa1 n/a
186 E1K248_GLY E1K248 cytochrome-c3 hydrogenase (EC n/a
187 A0A164UM01_GLY A0A164UM01 deleted n/a
188 P00960_GLY P00960 Glycine--tRNA ligase alpha n/a
189 O07051_GLY O07051 L-allo-threonine aldolase (L-allo-TA) n/a
190 Q9Y3Z3_GLY Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase n/a
191 G7ILW0_GLY G7ILW0 Serine hydroxymethyltransferase (EC n/a
192 P0DTD1_GLY P0DTD1 Replicase polyprotein 1ab n/a
193 P03952_GLY P03952 Plasma kallikrein (EC n/a
194 Q9P371_GLY Q9P371 AMSH-like protease sst2 n/a
195 B7J3C9_GLY B7J3C9 Tetrathionate hydrolase (4THase) n/a
196 P81446_GLY P81446 Beta-galactoside-specific lectin 1 n/a
197 Q96DA2_GLY Q96DA2 Ras-related protein Rab-39B n/a
198 Q47UY5_GLY Q47UY5 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
199 P06276_GLY P06276 Cholinesterase (EC 3.1.1.8) n/a
200 Q13976_GLY Q13976 cGMP-dependent protein kinase n/a
201 Q9NXG6_GLY Q9NXG6 Transmembrane prolyl 4-hydroxylase n/a
202 P74416_GLY P74416 Glycine dehydrogenase (decarboxylating) n/a
203 A0A380PV03_GLY A0A380PV03 Transporter, sodium/bile acid n/a
204 P60022_GLY P60022 Beta-defensin 1 (BD-1) n/a
205 Q5L3C7_GLY Q5L3C7 Phosphoribosylamine--glycine ligase (EC n/a
206 P27150_GLY P27150 Large ribosomal subunit n/a
207 P34897_GLY P34897 Serine hydroxymethyltransferase, mitochondrial product of
208 F8W4B7_GLY F8W4B7 Histone deacetylase 6 n/a
209 C0KD15_GLY C0KD15 Glutamate receptor ionotropic, n/a
210 E1K247_GLY E1K247 Nickel-dependent hydrogenase large n/a