Ligand name: FOLIC ACID
PDB ligand accession: FOL
DrugBank: DB00158
PubChem: 6037;5280354;135398658;
ChEMBL: CHEMBL1622
InChI Key: OVBPIULPVIDEAO-LBPRGKRZSA-N
SMILES: c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCc2cnc3c(n2)C(=O)N=C(N3)N

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organic acids and derivatives
    • Class: Carboxylic acids and derivatives
      • Subclass: Amino acids, peptides, and analogues

List of proteins that are targets for DB00158

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P16184_FOL	P16184	Dihydrofolate reductase (EC	n/a
2	P00379_FOL	P00379	Dihydrofolate reductase (EC	n/a
3	P41439_FOL	P41439	Folate receptor gamma	binder
4	C3TR70_FOL	C3TR70	Dihydrofolate reductase (EC	n/a
5	A0A140AYW5_FOL	A0A140AYW5	Spike glycoprotein (S	n/a
6	Q07422_FOL	Q07422	Bifunctional dihydrofolate reductase-thymidylate	n/a
7	Q9AGP8_FOL	Q9AGP8	Dimethylglycine oxidase (DMGO)	n/a
8	Q83AB2_FOL	Q83AB2	Dihydrofolate reductase (EC	n/a
9	B1XC49_FOL	B1XC49	deleted	n/a
10	A0A061BQC9_FOL	A0A061BQC9	deleted	n/a
11	A0A164XFT9_FOL	A0A164XFT9	deleted	n/a
12	P0ABQ4_FOL	P0ABQ4	Dihydrofolate reductase (EC	n/a
13	Q70YQ6_FOL	Q70YQ6	Dihydrofolate reductase (EC	n/a
14	T2B999_FOL	T2B999	Spike glycoprotein (S	n/a
15	P14207_FOL	P14207	Folate receptor beta	binder
16	P00383_FOL	P00383	Dihydrofolate reductase type	n/a
17	Q27552_FOL	Q27552	Bifunctional dihydrofolate reductase-thymidylate	n/a
18	Q1RGF0_FOL	Q1RGF0	dihydrofolate reductase (EC	n/a
19	U6N356_FOL	U6N356	deleted	n/a
20	P15328_FOL	P15328	Folate receptor alpha	n/a
21	O76290_FOL	O76290	Pteridine reductase	n/a
22	K0BRG7_FOL	K0BRG7	Spike glycoprotein (S	n/a
23	Q837A3_FOL	Q837A3	Folate family ECF	n/a
24	Q01782_FOL	Q01782	Pteridine reductase 1	n/a
25	J9F199_FOL	J9F199	dihydrofolate reductase (EC	n/a
26	P00374_FOL	P00374	Dihydrofolate reductase (EC	n/a
27	Q2RM91_FOL	Q2RM91	Formate--tetrahydrofolate ligase (EC	n/a
28	A0A1Z4A6S6_FOL	A0A1Z4A6S6	deleted	n/a
29	A0A0N8R1B2_FOL	A0A0N8R1B2	Methionyl-tRNA formyltransferase	n/a