Ligand name: Tramadol
PDB ligand accession: n/a
DrugBank: DB00193
InChI Key:
SMILES: COC1=CC=CC(=C1)C1(O)CCCCC1CN(C)C

List of proteins that are targets for DB00193

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P28335_DB00193 P28335 5-hydroxytryptamine receptor 2C antagonist
2 Q99250_DB00193 Q99250 Sodium channel protein inhibitor
3 P41143_DB00193 P41143 Delta-type opioid receptor agonist Ki(nM) = 9.4
4 P25103_DB00193 P25103 Substance-P receptor (SPR) inhibitor
5 P11229_DB00193 P11229 Muscarinic acetylcholine receptor antagonist
6 P23975_DB00193 P23975 Sodium-dependent noradrenaline transporter inhibitor IC50(nM) = 790.0
7 Q8NER1_DB00193 Q8NER1 Transient receptor potential agonist
8 P35372_DB00193 P35372 Mu-type opioid receptor agonist Ki(nM) = 1600.0
IC50(nM) = 5300.0
EC50(nM) = 1000.0
9 P31645_DB00193 P31645 Sodium-dependent serotonin transporter inhibitor IC50(nM) = 1100.0
10 P30542_DB00193 P30542 Adenosine receptor A1 agonist
11 P20309_DB00193 P20309 Muscarinic acetylcholine receptor antagonist
12 P41145_DB00193 P41145 Kappa-type opioid receptor agonist Ki(nM) = 14.0