Ligand name: Ziprasidone
PDB ligand accession: n/a
DrugBank: DB00246
InChI Key: MVWVFYHBGMAFLY-UHFFFAOYSA-N
SMILES: c1ccc2c(c1)c(ns2)N3CCN(CC3)CCc4cc5c(cc4Cl)NC(=O)C5

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Diazinanes
      • Subclass: Piperazines

List of proteins that are targets for DB00246

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P20309_DB00246	P20309	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 1300.0
2	P08913_DB00246	P08913	Alpha-2A adrenergic receptor	antagonist	Ki(nM) = 154.0
3	P28223_DB00246	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 0.08 IC50(nM) = 0.42
4	P08912_DB00246	P08912	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 1600.0
5	P35462_DB00246	P35462	D(3) dopamine receptor	antagonist	Ki(nM) = 1.1
6	P11229_DB00246	P11229	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 300.0
7	P28222_DB00246	P28222	5-hydroxytryptamine receptor 1B	antagonist	Ki(nM) = 0.99
8	P28221_DB00246	P28221	5-hydroxytryptamine receptor 1D	antagonist	Ki(nM) = 2.4
9	P35348_DB00246	P35348	Alpha-1A adrenergic receptor	antagonist	Ki(nM) = 2.6 IC50(nM) = 11.0
10	P14416_DB00246	P14416	D(2) dopamine receptor	antagonist	Ki(nM) = 0.8 IC50(nM) = 5.0
11	P50406_DB00246	P50406	5-hydroxytryptamine receptor 6	antagonist	Ki(nM) = 20.0
12	P28335_DB00246	P28335	5-hydroxytryptamine receptor 2C	antagonist	Ki(nM) = 0.55
13	P21917_DB00246	P21917	D(4) dopamine receptor	antagonist	Ki(nM) = 0.8
14	P08173_DB00246	P08173	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 1600.0
15	P21728_DB00246	P21728	D(1A) dopamine receptor	antagonist	Ki(nM) = 9.5
16	P21918_DB00246	P21918	D(1B) dopamine receptor	antagonist
17	P18825_DB00246	P18825	Alpha-2C adrenergic receptor	antagonist	Ki(nM) = 59.0
18	P34969_DB00246	P34969	5-hydroxytryptamine receptor 7	antagonist	Ki(nM) = 5.0
19	P35367_DB00246	P35367	Histamine H1 receptor	antagonist	Ki(nM) = 4.6
20	P18089_DB00246	P18089	Alpha-2B adrenergic receptor	antagonist	Ki(nM) = 48.0
21	P47898_DB00246	P47898	5-hydroxytryptamine receptor 5A	antagonist
22	P28566_DB00246	P28566	5-hydroxytryptamine receptor 1E	antagonist	Ki(nM) = 360.0
23	P08908_DB00246	P08908	5-hydroxytryptamine receptor 1A	agonist	Ki(nM) = 1.6
24	P08172_DB00246	P08172	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 2440.0
25	P35368_DB00246	P35368	Alpha-1B adrenergic receptor	antagonist