Ligand name: Olanzapine
PDB ligand accession: n/a
DrugBank: DB00334
InChI Key:
SMILES: CN1CCN(CC1)C1=NC2=CC=CC=C2NC2=C1C=C(C)S2

List of proteins that are targets for DB00334

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P21917_DB00334	P21917	D(4) dopamine receptor	antagonist	Ki(nM) = 20.0 IC50(nM) = 173.0
2	P35367_DB00334	P35367	Histamine H1 receptor	antagonist	Ki(nM) = 1.2 Kd(nM) = 0.087
3	P20309_DB00334	P20309	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 26.0
4	P11229_DB00334	P11229	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 2.1 EC50(nM) = 100000.0
5	P28335_DB00334	P28335	5-hydroxytryptamine receptor 2C	antagonist	Ki(nM) = 2.8 IC50(nM) = 71.0
6	P08173_DB00334	P08173	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 13.0
7	P08172_DB00334	P08172	Muscarinic acetylcholine receptor	antagonist
8	P14416_DB00334	P14416	D(2) dopamine receptor	antagonist	Ki(nM) = 2.1 IC50(nM) = 10.0
9	P21918_DB00334	P21918	D(1B) dopamine receptor	antagonist
10	P35348_DB00334	P35348	Alpha-1A adrenergic receptor	antagonist	Ki(nM) = 15.0
11	P46098_DB00334	P46098	5-hydroxytryptamine receptor 3A	antagonist
12	P35368_DB00334	P35368	Alpha-1B adrenergic receptor	antagonist
13	P28223_DB00334	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 0.42 IC50(nM) = 7.0
14	P21728_DB00334	P21728	D(1A) dopamine receptor	antagonist	Ki(nM) = 10.0
15	P35462_DB00334	P35462	D(3) dopamine receptor	antagonist	Ki(nM) = 20.0
16	P50406_DB00334	P50406	5-hydroxytryptamine receptor 6	antagonist	Ki(nM) = 5.0