Ligand name: Clozapine
PDB ligand accession: n/a
DrugBank: DB00363
InChI Key: QZUDBNBUXVUHMW-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C2=Nc3cc(ccc3Nc4c2cccc4)Cl

List of proteins that are targets for DB00363

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P21917_DB00363	P21917	antagonist	Ki(nM) = 7.27 IC50(nM) = 17.0
2	P35368_DB00363	P35368	antagonist
3	P20309_DB00363	P20309	antagonist	Ki(nM) = 34.0 EC50(nM) = 10000.0
4	P35367_DB00363	P35367	antagonist	Ki(nM) = 1.0 Kd(nM) = 3.1
5	P46098_DB00363	P46098	antagonist	Ki(nM) = 186.0
6	P14416_DB00363	P14416	antagonist	Ki(nM) = 6.87 IC50(nM) = 9.0
7	P18825_DB00363	P18825	antagonist	Ki(nM) = 2.9
8	Q9H3N8_DB00363	Q9H3N8	agonist	Ki(nM) = 200.0 Kd(nM) = 11.9
9	P18089_DB00363	P18089	antagonist
10	P28221_DB00363	P28221	antagonist
11	P08173_DB00363	P08173	partial agonist	Ki(nM) = 13.0 EC50(nM) = 10000.0
12	P28222_DB00363	P28222	antagonist
13	P35462_DB00363	P35462	antagonist	Ki(nM) = 6.62 IC50(nM) = 450.0
14	P35348_DB00363	P35348	antagonist	Ki(nM) = 19.0
15	P11229_DB00363	P11229	partial agonist	Ki(nM) = 0.98 IC50(nM) = 9.4 EC50(nM) = 10000.0
16	P08172_DB00363	P08172	partial agonist	EC50(nM) = 10000.0
17	P28335_DB00363	P28335	antagonist	Ki(nM) = 2.9 IC50(nM) = 10.0
18	P08913_DB00363	P08913	antagonist	Ki(nM) = 24.0
19	P50406_DB00363	P50406	antagonist	Ki(nM) = 4.0 IC50(nM) = 17.0
20	P08912_DB00363	P08912	antagonist
21	P08908_DB00363	P08908	antagonist	Ki(nM) = 6.4 IC50(nM) = 150.0
22	P21728_DB00363	P21728	antagonist	Ki(nM) = 7.5
23	P34969_DB00363	P34969	antagonist	Ki(nM) = 9.0
24	P09211_DB00363	P09211	n/a
25	P28566_DB00363	P28566	antagonist
26	P28223_DB00363	P28223	antagonist	Ki(nM) = 1.4 IC50(nM) = 12.0