Ligand name: TACRINE
PDB ligand accession: THA
DrugBank: DB00382
PubChem: 1935
ChEMBL: CHEMBL95
InChI Key: YLJREFDVOIBQDA-UHFFFAOYSA-N
SMILES: c1ccc2c(c1)c(c3c(n2)CCCC3)N

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Quinolines and derivatives
      • Subclass: Benzoquinolines

List of proteins that are targets for DB00382

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P06276_THA	P06276	Cholinesterase (EC 3.1.1.8)	inhibitor	Ki(nM) = 7.0 IC50(nM) = 0.0267
2	P23141_THA	P23141	Liver carboxylesterase 1	n/a	Ki(nM) = 100000.0 IC50(nM) = 100000.0
3	P22303_THA	P22303	Acetylcholinesterase (AChE) (EC	inhibitor	Ki(nM) = 6.9 IC50(nM) = 3.16
4	P04058_THA	P04058	Acetylcholinesterase (AChE) (EC	n/a	Ki(nM) = 40.0 IC50(nM) = 8.2
5	P50135_THA	P50135	Histamine N-methyltransferase (HMT)	n/a