Ligand name: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
PDB ligand accession: Z80
DrugBank: DB00477
PubChem: 2726
ChEMBL: CHEMBL71
InChI Key: ZPEIMTDSQAKGNT-UHFFFAOYSA-N
SMILES: CN(C)CCCN1c2ccccc2Sc3c1cc(cc3)Cl

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Benzothiazines
      • Subclass: Phenothiazines

List of proteins that are targets for DB00477

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P35368_Z80	P35368	inhibitor
2	P21918_Z80	P21918	inhibitor	Ki(nM) = 133.0
3	P02638_Z80	P02638	n/a
4	P11229_Z80	P11229	antagonist	Ki(nM) = 25.0
5	P50406_Z80	P50406	binder	Ki(nM) = 4.0
6	Q9H3N8_Z80	Q9H3N8	binder	Ki(nM) = 50.2
7	P22535_Z80	P22535	n/a
8	P19652_Z80	P19652	binder
9	P21728_Z80	P21728	inhibitor	Ki(nM) = 44.0
10	P0DP23_Z80	P0DP23	inhibitor	Ki(nM) = 19280.0 IC50(nM) = 7260.0
11	P28223_Z80	P28223	antagonist	Ki(nM) = 1.8
12	P35348_Z80	P35348	antagonist	Ki(nM) = 0.28
13	Q9VWX8_Z80	Q9VWX8	n/a
14	P14416_Z80	P14416	antagonist	Ki(nM) = 0.66 IC50(nM) = 1.0
15	P35367_Z80	P35367	antagonist	Ki(nM) = 3.0 IC50(nM) = 12.0
16	P34969_Z80	P34969	binder	Ki(nM) = 11.0
17	P08908_Z80	P08908	antagonist	Ki(nM) = 116.4
18	P35462_Z80	P35462	inhibitor	Ki(nM) = 0.84
19	P17405_Z80	P17405	inhibitor	IC50(nM) = 11000.0
20	P04925_Z80	P04925	n/a	EC50(nM) = 2000.0
21	P02754_Z80	P02754	n/a
22	P21917_Z80	P21917	binder	Ki(nM) = 1.15
23	P28335_Z80	P28335	binder	Ki(nM) = 1.4
24	E0SJQ4_Z80	E0SJQ4	n/a
25	P20309_Z80	P20309	antagonist	Ki(nM) = 47.0
26	Q12809_Z80	Q12809	inhibitor	IC50(nM) = 1470.0