Ligand name: Amoxapine
PDB ligand accession: n/a
DrugBank: DB00543
InChI Key:
SMILES: ClC1=CC2=C(OC3=CC=CC=C3N=C2N2CCNCC2)C=C1

List of proteins that are targets for DB00543

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P35462_DB00543	P35462	D(3) dopamine receptor	antagonist	Ki(nM) = 11.0
2	Q9H3N8_DB00543	Q9H3N8	Histamine H4 receptor	binder	Ki(nM) = 5012.0
3	P50406_DB00543	P50406	5-hydroxytryptamine receptor 6	antagonist	Ki(nM) = 50.0
4	P14416_DB00543	P14416	D(2) dopamine receptor	antagonist	Ki(nM) = 3.6
5	P14867_DB00543	P14867	Gamma-aminobutyric acid receptor	antagonist
6	P08908_DB00543	P08908	5-hydroxytryptamine receptor 1A	antagonist	Ki(nM) = 221.0
7	P35367_DB00543	P35367	Histamine H1 receptor	antagonist
8	P46098_DB00543	P46098	5-hydroxytryptamine receptor 3A	antagonist
9	P31645_DB00543	P31645	Sodium-dependent serotonin transporter	inhibitor	Ki(nM) = 58.0
10	P23975_DB00543	P23975	Sodium-dependent noradrenaline transporter	inhibitor	Ki(nM) = 16.0
11	P41595_DB00543	P41595	5-hydroxytryptamine receptor 2B	antagonist
12	Q01959_DB00543	Q01959	Sodium-dependent dopamine transporter	binder	Ki(nM) = 4310.0
13	P08913_DB00543	P08913	Alpha-2A adrenergic receptor	antagonist
14	P34969_DB00543	P34969	5-hydroxytryptamine receptor 7	antagonist	Ki(nM) = 500.0
15	P35348_DB00543	P35348	Alpha-1A adrenergic receptor	antagonist
16	P28222_DB00543	P28222	5-hydroxytryptamine receptor 1B	antagonist
17	P28335_DB00543	P28335	5-hydroxytryptamine receptor 2C	antagonist
18	P11229_DB00543	P11229	Muscarinic acetylcholine receptor	antagonist
19	P21917_DB00543	P21917	D(4) dopamine receptor	antagonist	Ki(nM) = 2.0
20	P28223_DB00543	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 1.77
21	P21728_DB00543	P21728	D(1A) dopamine receptor	antagonist