Ligand name: Trazodone
PDB ligand accession: n/a
DrugBank: DB00656
InChI Key:
SMILES: ClC1=CC=CC(=C1)N1CCN(CCCN2N=C3C=CC=CN3C2=O)CC1

List of proteins that are targets for DB00656

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P28335_DB00656 P28335 5-hydroxytryptamine receptor 2C agonist Ki(nM) = 25.0
2 P35367_DB00656 P35367 Histamine H1 receptor antagonist Ki(nM) = 1100.0
3 P08908_DB00656 P08908 5-hydroxytryptamine receptor 1A antagonist Ki(nM) = 96.0
EC50(nM) = 785.0
4 P31645_DB00656 P31645 Sodium-dependent serotonin transporter inhibitor Ki(nM) = 160.0
5 P08913_DB00656 P08913 Alpha-2A adrenergic receptor antagonist Ki(nM) = 106.0
6 P35348_DB00656 P35348 Alpha-1A adrenergic receptor antagonist Ki(nM) = 12.0
7 P28223_DB00656 P28223 5-hydroxytryptamine receptor 2A antagonist Ki(nM) = 44.67
IC50(nM) = 243.0