Ligand name: (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE
PDB ligand accession: CTX
DrugBank: DB00675
PubChem: 2733526
ChEMBL: CHEMBL83
InChI Key: NKANXQFJJICGDU-QPLCGJKRSA-N
SMILES: CCC(=C(c1ccccc1)c2ccc(cc2)OCCN(C)C)c3ccccc3

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Phenylpropanoids and polyketides
    • Class: Stilbenes
      • Subclass: None

List of proteins that are targets for DB00675

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q92731_CTX	Q92731	Estrogen receptor beta	antagonist	Ki(nM) = 0.51 IC50(nM) = 5.0 EC50(nM) = 1000.0
2	Q15125_CTX	Q15125	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5)	inhibitor	Ki(nM) = 5.0 IC50(nM) = 12.0
3	A0L5S6_CTX	A0L5S6	Ion transport protein	n/a
4	P62508_CTX	P62508	Estrogen-related receptor gamma	n/a	IC50(nM) = 62.0
5	P04278_CTX	P04278	Sex hormone-binding globulin	inducer
6	P45983_CTX	P45983	Mitogen-activated protein kinase	modulator
7	Q12809_CTX	Q12809	Voltage-gated inwardly rectifying	inhibitor	IC50(nM) = 1584.89
8	P03372_CTX	P03372	Estrogen receptor (ER)	antagonist	Ki(nM) = 12.0 IC50(nM) = 1.5 EC50(nM) = 622.0
9	P10275_CTX	P10275	Androgen receptor (Dihydrotestosterone	n/a
10	O75469_CTX	O75469	Nuclear receptor subfamily	n/a
11	P23141_CTX	P23141	Liver carboxylesterase 1	n/a