Ligand name: 3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
PDB ligand accession: n/a
DrugBank: DB00734
InChI Key: RAPZEAPATHNIPO-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)c4c5ccc(cc5on4)F

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridopyrimidines
      • Subclass: None

List of proteins that are targets for DB00734

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P18825_DB00734	P18825	Alpha-2C adrenergic receptor	antagonist	Ki(nM) = 1.3
2	P35348_DB00734	P35348	Alpha-1A adrenergic receptor	antagonist	Ki(nM) = 0.7 IC50(nM) = 10.0
3	P18089_DB00734	P18089	Alpha-2B adrenergic receptor	antagonist	Ki(nM) = 8.5
4	P35367_DB00734	P35367	Histamine H1 receptor	antagonist	Ki(nM) = 2.6 IC50(nM) = 454.0
5	P21728_DB00734	P21728	D(1A) dopamine receptor	antagonist	Ki(nM) = 21.0
6	P28335_DB00734	P28335	5-hydroxytryptamine receptor 2C	antagonist	Ki(nM) = 2.4 IC50(nM) = 1.8
7	P34969_DB00734	P34969	5-hydroxytryptamine receptor 7	antagonist	Ki(nM) = 0.4
8	P28221_DB00734	P28221	5-hydroxytryptamine receptor 1D	antagonist	Ki(nM) = 3.9
9	P08908_DB00734	P08908	5-hydroxytryptamine receptor 1A	antagonist	Ki(nM) = 21.0 EC50(nM) = 10000.0
10	P14416_DB00734	P14416	D(2) dopamine receptor	antagonist	Ki(nM) = 0.3 IC50(nM) = 3.6
11	P35368_DB00734	P35368	Alpha-1B adrenergic receptor	antagonist
12	P28223_DB00734	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 0.14 IC50(nM) = 0.707946