Ligand name: Donepezil
PDB ligand accession: n/a
DrugBank: DB00843
InChI Key:
SMILES: COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1

List of proteins that are targets for DB00843

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P28223_DB00843 P28223 5-hydroxytryptamine receptor 2A inducer
2 P06276_DB00843 P06276 Cholinesterase (EC 3.1.1.8) inducer Ki(nM) = 640.0
IC50(nM) = 14.0
3 P22303_DB00843 P22303 Acetylcholinesterase (AChE) (EC inhibitor Ki(nM) = 2.9
IC50(nM) = 2.0
Kd(nM) = 8.0
EC50(nM) = 43.0
4 P98066_DB00843 P98066 Tumor necrosis factor-inducible inhibitor
5 P29475_DB00843 P29475 Nitric oxide synthase inhibitor
6 P01584_DB00843 P01584 Interleukin-1 beta (IL-1 inhibitor