Ligand name: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE
PDB ligand accession: ETS
DrugBank: DB00869
PubChem: 5284549
ChEMBL: CHEMBL218490
InChI Key: IAVUPMFITXYVAF-XPUUQOCRSA-N
SMILES: CCNC1CC(S(=O)(=O)c2c1cc(s2)S(=O)(=O)N)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Thiophenes
      • Subclass: 2,3,5-trisubstituted thiophenes

List of proteins that are targets for DB00869

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P22748_ETS	P22748	Carbonic anhydrase 4	inhibitor	Ki(nM) = 43.0 IC50(nM) = 32.0
2	P07451_ETS	P07451	Carbonic anhydrase 3	inhibitor	Ki(nM) = 8000.0
3	P00918_ETS	P00918	Carbonic anhydrase 2	inhibitor	Ki(nM) = 0.111 IC50(nM) = 0.23 Kd(nM) = 0.043
4	P00915_ETS	P00915	Carbonic anhydrase 1	inhibitor	Ki(nM) = 500.0 IC50(nM) = 1583.63