Ligand name: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
PDB ligand accession: GBM
DrugBank: DB01016
PubChem: 3488
ChEMBL: CHEMBL472
InChI Key: ZNNLBTZKUZBEKO-UHFFFAOYSA-N
SMILES: COc1ccc(cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3)Cl

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Benzenesulfonamides

List of proteins that are targets for DB01016

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	O95477_GBM	O95477	Phospholipid-transporting ATPase ABCA1	inhibitor
2	P50416_GBM	P50416	Carnitine O-palmitoyltransferase 1,	inhibitor
3	Q8I5R7_GBM	Q8I5R7	Proline--tRNA ligase (PfPRS)	n/a
4	A0A1U7R319_GBM	A0A1U7R319	ATP-binding cassette sub-family	n/a
5	Q04828_GBM	Q04828	Aldo-keto reductase family	n/a
6	P42330_GBM	P42330	Aldo-keto reductase family	n/a
7	Q8TD43_GBM	Q8TD43	Transient receptor potential	inhibitor
8	P13569_GBM	P13569	Cystic fibrosis transmembrane	antagonist	IC50(nM) = 15000.0
9	O60706_GBM	O60706	ATP-binding cassette sub-family	modulator
10	O95342_GBM	O95342	Bile salt export	inhibitor	Ki(nM) = 27500.0 IC50(nM) = 1500.0