Ligand name: Nefazodone
PDB ligand accession: n/a
DrugBank: DB01149
InChI Key:
SMILES: CCC1=NN(CCCN2CCN(CC2)C2=CC(Cl)=CC=C2)C(=O)N1CCOC1=CC=CC=C1

List of proteins that are targets for DB01149

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P23975_DB01149 P23975 Sodium-dependent noradrenaline transporter inhibitor Ki(nM) = 360.0
Kd(nM) = 360.0
2 P08913_DB01149 P08913 Alpha-2A adrenergic receptor antagonist Ki(nM) = 84.0
3 Q12809_DB01149 Q12809 Voltage-gated inwardly rectifying antagonist
4 P35368_DB01149 P35368 Alpha-1B adrenergic receptor other/unknown
5 P28335_DB01149 P28335 5-hydroxytryptamine receptor 2C antagonist Ki(nM) = 26.0
6 Q01959_DB01149 Q01959 Sodium-dependent dopamine transporter inhibitor Ki(nM) = 360.0
Kd(nM) = 360.0
7 P31645_DB01149 P31645 Sodium-dependent serotonin transporter inhibitor Ki(nM) = 200.0
Kd(nM) = 200.0
8 P28223_DB01149 P28223 5-hydroxytryptamine receptor 2A antagonist Ki(nM) = 5.8
9 P08908_DB01149 P08908 5-hydroxytryptamine receptor 1A antagonist Ki(nM) = 80.0
10 P35348_DB01149 P35348 Alpha-1A adrenergic receptor antagonist Ki(nM) = 5.5