Ligand name: 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE
PDB ligand accession: DSM
DrugBank: DB01151
PubChem: 2995
ChEMBL: CHEMBL72
InChI Key: HCYAFALTSJYZDH-UHFFFAOYSA-N
SMILES: CNCCCN1c2ccccc2CCc3c1cccc3

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Benzazepines
      • Subclass: Dibenzazepines

List of proteins that are targets for DB01151

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P07550_DSM	P07550	Beta-2 adrenergic receptor	antagonist
2	P31645_DSM	P31645	Sodium-dependent serotonin transporter	inhibitor	Ki(nM) = 17.6 IC50(nM) = 64.0
3	P28223_DSM	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 160.0
4	P08912_DSM	P08912	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 143.0
5	P08173_DSM	P08173	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 160.0
6	P08908_DSM	P08908	5-hydroxytryptamine receptor 1A	binder	Ki(nM) = 6400.0
7	P35367_DSM	P35367	Histamine H1 receptor	antagonist	Ki(nM) = 60.0
8	P23975_DSM	P23975	Sodium-dependent noradrenaline transporter	inhibitor	Ki(nM) = 0.49 IC50(nM) = 0.93 Kd(nM) = 0.83
9	O67854_DSM	O67854	Na(+):neurotransmitter symporter (Snf	n/a
10	P14416_DSM	P14416	D(2) dopamine receptor	binder	Ki(nM) = 1561.0
11	P17405_DSM	P17405	Sphingomyelin phosphodiesterase (EC	inhibitor
12	P02754_DSM	P02754	Beta-lactoglobulin (Beta-LG) (allergen	n/a
13	P20309_DSM	P20309	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 210.0
14	P08172_DSM	P08172	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 66.0
15	P28335_DSM	P28335	5-hydroxytryptamine receptor 2C	binder	Ki(nM) = 350.0
16	P11229_DSM	P11229	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 110.0
17	P08588_DSM	P08588	Beta-1 adrenergic receptor	other