Ligand name: Quetiapine
PDB ligand accession: n/a
DrugBank: DB01224
InChI Key:
SMILES: OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C12

List of proteins that are targets for DB01224

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P18825_DB01224 P18825 Alpha-2C adrenergic receptor antagonist Ki(nM) = 28.7
2 P11229_DB01224 P11229 Muscarinic acetylcholine receptor antagonist Ki(nM) = 56.0
EC50(nM) = 10000.0
3 P34969_DB01224 P34969 5-hydroxytryptamine receptor 7 ligand Ki(nM) = 63.0
4 P08172_DB01224 P08172 Muscarinic acetylcholine receptor ligand Ki(nM) = 630.0
5 P08173_DB01224 P08173 Muscarinic acetylcholine receptor ligand Ki(nM) = 126.0
6 P28335_DB01224 P28335 5-hydroxytryptamine receptor 2C ligand Ki(nM) = 615.0
7 P08908_DB01224 P08908 5-hydroxytryptamine receptor 1A antagonist Ki(nM) = 79.0
8 P28222_DB01224 P28222 5-hydroxytryptamine receptor 1B ligand Ki(nM) = 2050.0
9 P21917_DB01224 P21917 D(4) dopamine receptor ligand Ki(nM) = 500.0
10 P28221_DB01224 P28221 5-hydroxytryptamine receptor 1D ligand Ki(nM) = 560.0
11 P14416_DB01224 P14416 D(2) dopamine receptor antagonist Ki(nM) = 16.0
12 P21918_DB01224 P21918 D(1B) dopamine receptor ligand Ki(nM) = 1513.0
13 P50406_DB01224 P50406 5-hydroxytryptamine receptor 6 antagonist Ki(nM) = 33.0
14 P46098_DB01224 P46098 5-hydroxytryptamine receptor 3A ligand
15 P28566_DB01224 P28566 5-hydroxytryptamine receptor 1E ligand Ki(nM) = 1250.0
16 P18089_DB01224 P18089 Alpha-2B adrenergic receptor antagonist Ki(nM) = 90.0
17 P35367_DB01224 P35367 Histamine H1 receptor antagonist Ki(nM) = 2.2
18 P20309_DB01224 P20309 Muscarinic acetylcholine receptor antagonist Ki(nM) = 705.0
19 P08913_DB01224 P08913 Alpha-2A adrenergic receptor antagonist Ki(nM) = 80.0
20 P08912_DB01224 P08912 Muscarinic acetylcholine receptor ligand Ki(nM) = 2990.0
21 P21728_DB01224 P21728 D(1A) dopamine receptor antagonist Ki(nM) = 390.0
22 P28223_DB01224 P28223 5-hydroxytryptamine receptor 2A antagonist Ki(nM) = 31.0
23 P35462_DB01224 P35462 D(3) dopamine receptor ligand Ki(nM) = 9.2