Ligand name: DEXAMETHASONE
PDB ligand accession: DEX
DrugBank: DB01234
PubChem: 5743
ChEMBL: CHEMBL384467
InChI Key: UREBDLICKHMUKA-CXSFZGCWSA-N
SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Lipids and lipid-like molecules
    • Class: Steroids and steroid derivatives
      • Subclass: Hydroxysteroids

List of proteins that are targets for DB01234

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P51843_DEX	P51843	stimulator
2	P35228_DEX	P35228	negative modulator
3	P08235_DEX	P08235	n/a	Ki(nM) = 0.36 IC50(nM) = 33.0
4	P04083_DEX	P04083	agonist
5	O75469_DEX	O75469	agonist
6	P35747_DEX	P35747	n/a
7	A0A1X8XLE9_DEX	A0A1X8XLE9	n/a
8	P06537_DEX	P06537	n/a
9	P04150_DEX	P04150	agonist	Ki(nM) = 0.69 IC50(nM) = 0.5 Kd(nM) = 2.0 EC50(nM) = 0.1