PDB ligand accession: n/a
DrugBank: DB01392
InChI Key:
SMILES: [H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2
| # | DrugDomain Data | UniProt Accession | Protein name | Drug Action | Affinity data |
|---|---|---|---|---|---|
| 1 | P14416_DB01392 | P14416 | D(2) dopamine receptor | antagonist | Ki(nM) = 280.0 |
| 2 | P41595_DB01392 | P41595 | 5-hydroxytryptamine receptor 2B | antagonist | Ki(nM) = 4.12 |
| 3 | P18825_DB01392 | P18825 | Alpha-2C adrenergic receptor | antagonist | Ki(nM) = 0.13 IC50(nM) = 27.1 |
| 4 | P28335_DB01392 | P28335 | 5-hydroxytryptamine receptor 2C | antagonist | Ki(nM) = 645.65 |
| 5 | P28223_DB01392 | P28223 | 5-hydroxytryptamine receptor 2A | antagonist | Ki(nM) = 252.0 |
| 6 | P28221_DB01392 | P28221 | 5-hydroxytryptamine receptor 1D | partial agonist | Ki(nM) = 15.84 |
| 7 | P18089_DB01392 | P18089 | Alpha-2B adrenergic receptor | antagonist | Ki(nM) = 0.32 |
| 8 | P28222_DB01392 | P28222 | 5-hydroxytryptamine receptor 1B | partial agonist | Ki(nM) = 5.0 |
| 9 | P35462_DB01392 | P35462 | D(3) dopamine receptor | antagonist | Ki(nM) = 2489.0 |
| 10 | P08908_DB01392 | P08908 | 5-hydroxytryptamine receptor 1A | partial agonist | Ki(nM) = 50.11 |
| 11 | P08913_DB01392 | P08913 | Alpha-2A adrenergic receptor | antagonist | Ki(nM) = 0.32 IC50(nM) = 3.67 Kd(nM) = 2300.0 EC50(nM) = 8.5 |