Ligand name: Yohimbine
PDB ligand accession: n/a
DrugBank: DB01392
InChI Key:
SMILES: [H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2

List of proteins that are targets for DB01392

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P14416_DB01392 P14416 D(2) dopamine receptor antagonist Ki(nM) = 280.0
2 P41595_DB01392 P41595 5-hydroxytryptamine receptor 2B antagonist Ki(nM) = 4.12
3 P18825_DB01392 P18825 Alpha-2C adrenergic receptor antagonist Ki(nM) = 0.13
IC50(nM) = 27.1
4 P28335_DB01392 P28335 5-hydroxytryptamine receptor 2C antagonist Ki(nM) = 645.65
5 P28223_DB01392 P28223 5-hydroxytryptamine receptor 2A antagonist Ki(nM) = 252.0
6 P28221_DB01392 P28221 5-hydroxytryptamine receptor 1D partial agonist Ki(nM) = 15.84
7 P18089_DB01392 P18089 Alpha-2B adrenergic receptor antagonist Ki(nM) = 0.32
8 P28222_DB01392 P28222 5-hydroxytryptamine receptor 1B partial agonist Ki(nM) = 5.0
9 P35462_DB01392 P35462 D(3) dopamine receptor antagonist Ki(nM) = 2489.0
10 P08908_DB01392 P08908 5-hydroxytryptamine receptor 1A partial agonist Ki(nM) = 50.11
11 P08913_DB01392 P08913 Alpha-2A adrenergic receptor antagonist Ki(nM) = 0.32
IC50(nM) = 3.67
Kd(nM) = 2300.0
EC50(nM) = 8.5