Ligand name: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID
PDB ligand accession: FLF
DrugBank: DB02266
PubChem: 3371
ChEMBL: CHEMBL23588
InChI Key: LPEPZBJOKDYZAD-UHFFFAOYSA-N
SMILES: c1ccc(c(c1)C(=O)O)Nc2cccc(c2)C(F)(F)F

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Benzoic acids and derivatives

List of proteins that are targets for DB02266

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P10275_FLF	P10275	Androgen receptor (Dihydrotestosterone	inhibitor	IC50(nM) = 50000.0 EC50(nM) = 67000.0
2	P37231_FLF	P37231	Peroxisome proliferator-activated receptor	agonist
3	P02766_FLF	P02766	Transthyretin (ATTR) (Prealbumin)	n/a	IC50(nM) = 2900.0 Kd(nM) = 30.0
4	O60218_FLF	O60218	Aldo-keto reductase family	n/a	IC50(nM) = 760.0
5	P23219_FLF	P23219	Prostaglandin G/H synthase	inhibitor	IC50(nM) = 2230.0
6	Q15562_FLF	Q15562	Transcriptional enhancer factor	n/a
7	P35354_FLF	P35354	Prostaglandin G/H synthase	inhibitor	IC50(nM) = 16.0
8	Q07869_FLF	Q07869	Peroxisome proliferator-activated receptor	activator
9	P42330_FLF	P42330	Aldo-keto reductase family	inhibitor	Ki(nM) = 140.0 IC50(nM) = 50.0