Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 5'-DEOXY-5'-METHYLTHIOADENOSINE
PDB ligand accession: MTA
DrugBank: DB02282
PubChem: 439176
ChEMBL: CHEMBL277041
InChI Key: WUUGFSXJNOTRMR-IOSLPCCCSA-N
SMILES: CSCC1C(C(C(O1)n2cnc3c2ncnc3N)O)O

ClassyFire chemical classification:

List of proteins that are targets for DB02282

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P0DTD1_MTA P0DTD1 Replicase polyprotein 1ab n/a
2 O58832_MTA O58832 2-(3-amino-3-carboxypropyl)histidine synthase (EC n/a
3 Q5SLL8_MTA Q5SLL8 RNA 2'-O ribose n/a
4 O58523_MTA O58523 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase n/a
5 Q57564_MTA Q57564 L-aspartate semialdehyde sulfurtransferase n/a
6 O14744_MTA O14744 Protein arginine N-methyltransferase n/a
7 O58214_MTA O58214 tRNA (cytidine(56)-2'-O)-methyltransferase (EC n/a
8 P83816_MTA P83816 Polyamine aminopropyltransferase (Agmatine n/a
9 A5UMY5_MTA A5UMY5 2-(3-amino-3-carboxypropyl)histidine synthase (EC n/a
10 Q9ZMY2_MTA Q9ZMY2 Aminodeoxyfutalosine nucleosidase (AFL n/a
11 P50389_MTA P50389 Purine nucleoside phosphorylase n/a
12 Q7NZ90_MTA Q7NZ90 5-methylthioadenosine/S-adenosylhomocysteine deaminase (MTA/SAH n/a
13 Q12314_MTA Q12314 Protein arginine N-methyltransferase n/a
14 A3MU81_MTA A3MU81 Polyamine aminopropyltransferase (Putrescine n/a
15 P23686_MTA P23686 S-adenosylmethionine synthase 1 n/a
16 Q4VSJ8_MTA Q4VSJ8 Acyl-homoserine-lactone synthase (EC n/a
17 Q13126_MTA Q13126 S-methyl-5'-thioadenosine phosphorylase (EC n/a
18 B0B7H9_MTA B0B7H9 deleted n/a
19 Q5JIZ3_MTA Q5JIZ3 N(4)-bis(aminopropyl)spermidine synthase (EC n/a
20 P52788_MTA P52788 Spermine synthase (SPMSY) n/a
21 Q8Y8D7_MTA Q8Y8D7 NAD kinase 1 n/a
22 Q9V2G1_MTA Q9V2G1 tRNA (guanine(37)-N(1))/4-demethylwyosine(37)-methyltransferase Taw22 n/a
23 P24247_MTA P24247 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
24 G7K2D1_MTA G7K2D1 thermospermine synthase (EC n/a
25 O24915_MTA O24915 Aminodeoxyfutalosine nucleosidase (AFL n/a
26 A0A062UZ78_MTA A0A062UZ78 2-(3-amino-3-carboxypropyl)histidine synthase (EC n/a
27 B8NJH3_MTA B8NJH3 O-methyltransferase lepI (EC n/a
28 A0A0N0C224_MTA A0A0N0C224 deleted n/a
29 Q72G96_MTA Q72G96 Putative tRNA (cytidine(34)-2'-O)-methyltransferase n/a
30 I0B503_MTA I0B503 S-methyl-5'-thioadenosine phosphorylase (EC n/a
31 Q5SM60_MTA Q5SM60 Ribosomal RNA small n/a
32 P14751_MTA P14751 Type II methyltransferase n/a
33 P19623_MTA P19623 Spermidine synthase (SPDSY) n/a
34 E0PXI9_MTA E0PXI9 deleted n/a
35 P22087_MTA P22087 rRNA 2'-O-methyltransferase fibrillarin n/a
36 Q8DLC2_MTA Q8DLC2 Lipoyl synthase 2 n/a
37 Q4JB16_MTA Q4JB16 tRNA (cytidine-2'-O-)-methyltransferase TrmJ n/a
38 W4J0F1_MTA W4J0F1 Chaperone DnaK n/a
39 A0KGU9_MTA A0KGU9 MTA/SAH nucleosidase (EC n/a
40 Q72L89_MTA Q72L89 N(4)-bis(aminopropyl)spermidine synthase (EC n/a
41 Q31QK9_MTA Q31QK9 Polyamine aminopropyltransferase (Putrescine n/a
42 Q97W94_MTA Q97W94 S-methyl-5'-thioadenosine phosphorylase (EC n/a
43 Q8II73_MTA Q8II73 Spermidine synthase (EC n/a
44 O57950_MTA O57950 Polyamine aminopropyltransferase (Putrescine n/a
45 O26771_MTA O26771 Methyltransferase n/a
46 A0A0H3JXA8_MTA A0A0H3JXA8 D-histidine 2-aminobutanoyltransferase (EC n/a
47 P31153_MTA P31153 S-adenosylmethionine synthase isoform n/a
48 A0A031WG99_MTA A0A031WG99 site-specific DNA-methyltransferase (adenine-specific) n/a