Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: GUANINE
PDB ligand accession: GUN
DrugBank: DB02377
PubChem: 764;5274253;135398634;
ChEMBL: CHEMBL219568
InChI Key: UYTPUPDQBNUYGX-UHFFFAOYSA-N
SMILES: c1[nH]c2c(n1)C(=O)NC(=N2)N

ClassyFire chemical classification:

List of proteins that are targets for DB02377

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P80457_GUN P80457 Xanthine dehydrogenase/oxidase [Includes: n/a
2 D9J2T9_GUN D9J2T9 rRNA N-glycosylase (EC n/a
3 A0A376T1I0_GUN A0A376T1I0 deleted n/a
4 P0A9M5_GUN P0A9M5 Xanthine-guanine phosphoribosyltransferase (XGPRT) n/a
5 A1L259_GUN A1L259 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU n/a
6 O58843_GUN O58843 tRNA-guanine(15) transglycosylase (EC n/a
7 P0A7N4_GUN P0A7N4 Large ribosomal subunit n/a
8 A6Y463_GUN A6Y463 deleted n/a
9 P28720_GUN P28720 Queuine tRNA-ribosyltransferase (EC n/a
10 Q936X6_GUN Q936X6 ABC transporter substrate-binding n/a
11 Q03629_GUN Q03629 Uncharacterized protein YML079W n/a
12 C3LTF1_GUN C3LTF1 NADPH-dependent 7-cyano-7-deazaguanine reductase n/a
13 P30793_GUN P30793 GTP cyclohydrolase 1 inhibitor
14 Q2T1V0_GUN Q2T1V0 dihydroneopterin aldolase (EC n/a
15 P04632_GUN P04632 Calpain small subunit n/a
16 Q8V635_GUN Q8V635 Genome polyprotein [Cleaved n/a
17 Q00511_GUN Q00511 Uricase (EC 1.7.3.3) n/a
18 Q97MB6_GUN Q97MB6 guanine deaminase (EC n/a
19 P07132_GUN P07132 Core protein VP4 n/a
20 P45563_GUN P45563 Purine nucleoside phosphorylase n/a
21 P10297_GUN P10297 Antiviral protein I n/a
22 O55236_GUN O55236 mRNA-capping enzyme (HCE) n/a
23 Q89NG0_GUN Q89NG0 Guanine deaminase (Guanase) n/a
24 P00491_GUN P00491 Purine nucleoside phosphorylase n/a
25 Q6CSZ6_GUN Q6CSZ6 Purine nucleoside phosphorylase n/a
26 Q9X1T2_GUN Q9X1T2 Purine nucleoside phosphorylase n/a
27 P0DTC9_GUN P0DTC9 Nucleoprotein (N) (Nucleocapsid n/a
28 P60438_GUN P60438 Large ribosomal subunit n/a
29 Q9SF23_GUN Q9SF23 Dihydroneopterin aldolase 1 n/a
30 Q47WB4_GUN Q47WB4 Putative membrane protein n/a
31 Q0PA35_GUN Q0PA35 Bifunctional protein FolD n/a
32 P0ACP7_GUN P0ACP7 HTH-type transcriptional repressor n/a