Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
PDB ligand accession: CMP
DrugBank: DB02527
PubChem: 6076
ChEMBL: CHEMBL316966
InChI Key: IVOMOUWHDPKRLL-KQYNXXCUSA-N
SMILES: c1nc(c2c(n1)n(cn2)C3C(C4C(O3)COP(=O)(O4)O)O)N

ClassyFire chemical classification:

List of proteins that are targets for DB02527

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P07900_CMP P07900 Heat shock protein n/a
2 P55222_CMP P55222 cAMP-activated global transcriptional n/a
3 Q9UL51_CMP Q9UL51 Potassium/sodium hyperpolarization-activated cyclic n/a
4 G0GA88_CMP G0GA88 Transcriptional regulator, Crp/Fnr n/a
5 P16094_CMP P16094 Ribosome-inactivating protein momordin n/a
6 P0ACK0_CMP P0ACK0 cAMP-activated global transcriptional n/a
7 Q6P5T7_CMP Q6P5T7 cGMP-dependent protein kinase n/a
8 Q5SID7_CMP Q5SID7 Cyclic AMP receptor n/a
9 A0QYW6_CMP A0QYW6 Universal stress protein n/a
10 Q9EQZ6_CMP Q9EQZ6 Rap guanine nucleotide n/a
11 Q7CH76_CMP Q7CH76 Adenylate cyclase 2 n/a
12 P00514_CMP P00514 cAMP-dependent protein kinase n/a
13 P94182_CMP P94182 Adenylate cyclase (EC n/a
14 Q8ZKF6_CMP Q8ZKF6 Acetyl-coenzyme A synthetase n/a
15 P0DTD1_CMP P0DTD1 Replicase polyprotein 1ab n/a
16 S8EY88_CMP S8EY88 Cyclic nucleotide-binding domain-containing n/a
17 Q79VI7_CMP Q79VI7 CRP-like cAMP-activated global n/a
18 E0RR11_CMP E0RR11 Cyclic nucleotide-binding domain-containing n/a
19 W8UA39_CMP W8UA39 UPF0173 metal-dependent hydrolase n/a
20 A0A0H2W086_CMP A0A0H2W086 Catabolite activator protein n/a
21 O60741_CMP O60741 Potassium/sodium hyperpolarization-activated cyclic n/a
22 P07278_CMP P07278 cAMP-dependent protein kinase n/a
23 Q98GN8_CMP Q98GN8 Cyclic nucleotide-gated potassium n/a
24 P0ACJ8_CMP P0ACJ8 DNA-binding transcriptional dual n/a
25 Q6MLN6_CMP Q6MLN6 Signal transduction protein n/a
26 O76977_CMP O76977 Hyperpolarization-activated (Ih) channel n/a
27 B5II98_CMP B5II98 Nitrogen regulatory protein n/a
28 Q08499_CMP Q08499 3',5'-cyclic-AMP phosphodiesterase 4D n/a
29 O05581_CMP O05581 Acetyltransferase Pat (EC n/a
30 Q14028_CMP Q14028 Cyclic nucleotide-gated channel n/a
31 P10644_CMP P10644 cAMP-dependent protein kinase n/a
32 Q92SD2_CMP Q92SD2 cAMP-binding protein-catabolite gene n/a
33 O88703_CMP O88703 Potassium/sodium hyperpolarization-activated cyclic n/a
34 O69644_CMP O69644 CRP-like cAMP-activated global n/a
35 Q385V6_CMP Q385V6 Protein kinase A n/a
36 Q96PN6_CMP Q96PN6 Adenylate cyclase type n/a
37 G8UY02_CMP G8UY02 deleted n/a
38 Q9Y3Q4_CMP Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic n/a
39 G4VPI6_CMP G4VPI6 deleted n/a
40 H7C677_CMP H7C677 Crp/Fnr family transcriptional n/a
41 P00516_CMP P00516 cGMP-dependent protein kinase n/a
42 P12369_CMP P12369 cAMP-dependent protein kinase n/a
43 P15266_CMP P15266 Nucleoside diphosphate kinase n/a
44 P73954_CMP P73954 Membrane-associated protein slr1513 n/a
45 Q13976_CMP Q13976 cGMP-dependent protein kinase n/a
46 P31323_CMP P31323 cAMP-dependent protein kinase n/a
47 Q1GZZ4_CMP Q1GZZ4 Cyclic nucleotide-binding domain n/a
48 O88704_CMP O88704 Potassium/sodium hyperpolarization-activated cyclic n/a
49 Q9TV66_CMP Q9TV66 Potassium/sodium hyperpolarization-activated cyclic n/a
50 P40136_CMP P40136 Calmodulin-sensitive adenylate cyclase n/a
51 Q9Y233_CMP Q9Y233 cAMP and cAMP-inhibited n/a
52 Q7KQK0_CMP Q7KQK0 cAMP-dependent protein kinase n/a
53 A0AAJ6N6K4_CMP A0AAJ6N6K4 DarR n/a
54 Q13237_CMP Q13237 cGMP-dependent protein kinase n/a
55 P29973_CMP P29973 Cyclic nucleotide-gated channel n/a
56 B7Z5J6_CMP B7Z5J6 cDNA FLJ56134, highly n/a
57 Q540U1_CMP Q540U1 Class B acid n/a
58 P24476_CMP P24476 Ribosome-inactivating protein dianthin-30 n/a
59 Q72MQ6_CMP Q72MQ6 cGMP-specific phosphodiesterase n/a