Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: NICOTINAMIDE
PDB ligand accession: NCA
DrugBank: DB02701
PubChem: 936
ChEMBL: CHEMBL1140
InChI Key: DFPAKSUCGFBDDF-UHFFFAOYSA-N
SMILES: c1cc(cnc1)C(=O)N

ClassyFire chemical classification:

List of proteins that are targets for DB02701

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P11439_NCA P11439 Exotoxin A (ETA) product of
2 P00760_NCA P00760 Serine protease 1 n/a
3 Q8IXJ6_NCA Q8IXJ6 NAD-dependent protein deacetylase n/a IC50(nM) = 1200.0
4 Q8K4Z3_NCA Q8K4Z3 NAD(P)H-hydrate epimerase (EC n/a
5 Q93NH4_NCA Q93NH4 (S)-6-hydroxynicotine oxidase (EC n/a
6 P06873_NCA P06873 Proteinase K (EC n/a
7 Q5NLA1_NCA Q5NLA1 NADH:flavin oxidoreductase/NADH oxidase n/a
8 Q8TLY9_NCA Q8TLY9 Globin-sensor domain-containing protein n/a
9 D0VWZ1_NCA D0VWZ1 Amidase (EC 3.5.1.4) n/a
10 P09874_NCA P09874 Poly [ADP-ribose] polymerase binder IC50(nM) = 50119.0
11 P43490_NCA P43490 Nicotinamide phosphoribosyltransferase (NAmPRTase) n/a
12 P06700_NCA P06700 NAD-dependent histone deacetylase n/a IC50(nM) = 50000.0
13 P16094_NCA P16094 Ribosome-inactivating protein momordin n/a
14 Q91WG0_NCA Q91WG0 Acylcarnitine hydrolase (ACH n/a
15 Q06198_NCA Q06198 RNA polymerase sigma-H n/a
16 P25321_NCA P25321 cAMP-dependent protein kinase n/a
17 P24627_NCA P24627 Lactotransferrin (Lactoferrin) (EC n/a
18 P29241_NCA P29241 ADP-ribosyl cyclase/cyclic ADP-ribose n/a
19 Q6RCR0_NCA Q6RCR0 SdeA n/a
20 A0A1L1QK40_NCA A0A1L1QK40 Cyclohexanone Monooxygenase from n/a
21 P00588_NCA P00588 Diphtheria toxin (DT) n/a
22 P01898_NCA P01898 H-2 class I n/a
23 Q97PM2_NCA Q97PM2 deleted n/a
24 P38107_NCA P38107 Sigma factor AlgU n/a
25 P63611_NCA P63611 Chorismate synthase (CS) n/a
26 Q8N6T7_NCA Q8N6T7 NAD-dependent protein deacylase n/a IC50(nM) = 45000.0
27 P41816_NCA P41816 NADPH dehydrogenase 3 n/a
28 P0DTD1_NCA P0DTD1 Replicase polyprotein 1ab n/a
29 P71817_NCA P71817 Steroid isomerase, putative n/a
30 Q7DM12_NCA Q7DM12 Abrin A-chain n/a
31 O30124_NCA O30124 NAD-dependent protein deacylase n/a
32 Q10588_NCA Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose product of
33 A3LT82_NCA A3LT82 NADPH dehydrogenase n/a
34 P00338_NCA P00338 L-lactate dehydrogenase A n/a
35 Q8N8N7_NCA Q8N8N7 Prostaglandin reductase 2 n/a
36 Q13451_NCA Q13451 Peptidyl-prolyl cis-trans isomerase n/a
37 P40261_NCA P40261 Nicotinamide N-methyltransferase (EC n/a
38 Q9NXA8_NCA Q9NXA8 NAD-dependent protein deacylase n/a IC50(nM) = 28000.0
39 P28907_NCA P28907 ADP-ribosyl cyclase/cyclic ADP-ribose n/a
40 P07896_NCA P07896 Peroxisomal bifunctional enzyme n/a
41 Q9WYW0_NCA Q9WYW0 NAD-dependent protein deacetylase n/a
42 O58586_NCA O58586 Uncharacterized protein PH0856 n/a
43 Q9HWU9_NCA Q9HWU9 Probable dehydrogenase n/a
44 P04977_NCA P04977 Pertussis toxin subunit n/a
45 P15879_NCA P15879 Mono-ADP-ribosyltransferase C3 (EC n/a
46 Q9H2K2_NCA Q9H2K2 Poly [ADP-ribose] polymerase n/a
47 Q41736_NCA Q41736 ferredoxin--NADP(+) reductase (EC n/a
48 P53686_NCA P53686 NAD-dependent protein deacetylase n/a IC50(nM) = 91000.0