Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]
PDB ligand accession: PLG
DrugBank: DB02824
PubChem: 445062
ChEMBL: n/a
InChI Key: FEVQWBMNLWUBTF-UHFFFAOYSA-N
SMILES: Cc1c(c(c(cn1)COP(=O)(O)O)CNCC(=O)O)O

ClassyFire chemical classification:

List of proteins that are targets for DB02824

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P18079_PLG P18079 5-aminolevulinate synthase (EC n/a
2 Q9KM65_PLG Q9KM65 CAI-1 autoinducer synthase n/a
3 Q0K313_PLG Q0K313 2-amino-3-ketobutyrate coenzyme A n/a
4 P11926_PLG P11926 Ornithine decarboxylase (ODC) inhibitor
5 Q5M0B4_PLG Q5M0B4 Serine hydroxymethyltransferase (SHMT) n/a
6 Q84AR1_PLG Q84AR1 L-methionine gamma-lyase (EC n/a
7 P34897_PLG P34897 Serine hydroxymethyltransferase, mitochondrial n/a
8 P23378_PLG P23378 Glycine dehydrogenase (decarboxylating), n/a
9 P50431_PLG P50431 Serine hydroxymethyltransferase, cytosolic n/a
10 E7U392_PLG E7U392 deleted n/a
11 A0A133CK16_PLG A0A133CK16 Serine hydroxymethyltransferase (SHMT) n/a
12 A0A1G4H5I1_PLG A0A1G4H5I1 glycine hydroxymethyltransferase (EC n/a
13 O07051_PLG O07051 L-allo-threonine aldolase (L-allo-TA) n/a
14 P34896_PLG P34896 Serine hydroxymethyltransferase, cytosolic n/a
15 G7ILW0_PLG G7ILW0 Serine hydroxymethyltransferase (EC n/a
16 K4FW35_PLG K4FW35 Serine hydroxymethyltransferase (EC n/a
17 A0A0R0IK90_PLG A0A0R0IK90 Serine hydroxymethyltransferase (EC n/a
18 P75823_PLG P75823 Low specificity L-threonine n/a
19 P0A825_PLG P0A825 Serine hydroxymethyltransferase (SHMT) n/a
20 A0A4Q8MG35_PLG A0A4Q8MG35 deleted n/a
21 Q9X266_PLG Q9X266 L-allo-threonine aldolase n/a
22 A5K8L9_PLG A5K8L9 glycine hydroxymethyltransferase (EC n/a
23 P07511_PLG P07511 Serine hydroxymethyltransferase, cytosolic n/a
24 A7BFV6_PLG A7BFV6 Serine palmitoyltransferase (SPT) n/a
25 P07805_PLG P07805 Ornithine decarboxylase (ODC) n/a
26 C8W9P2_PLG C8W9P2 Cysteine desulfurase (EC n/a
27 K4FZF8_PLG K4FZF8 Serine hydroxymethyltransferase (EC n/a