Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
PDB ligand accession: DTP
DrugBank: DB03222
PubChem: 15993
ChEMBL: CHEMBL335538
InChI Key: SUYVUBYJARFZHO-RRKCRQDMSA-N
SMILES: c1nc(c2c(n1)n(cn2)C3CC(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)N

ClassyFire chemical classification:

List of proteins that are targets for DB03222

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P12689_DTP P12689 DNA repair protein n/a
2 Q9Y3Z3_DTP Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase n/a
3 P23921_DTP P23921 Ribonucleoside-diphosphate reductase large n/a
4 B6YWB8_DTP B6YWB8 CRISPR system single-strand-specific n/a
5 Q93IG4_DTP Q93IG4 Deoxyguanosine kinase (EC n/a
6 P11021_DTP P11021 Endoplasmic reticulum chaperone n/a
7 P03692_DTP P03692 DNA helicase/primase (EC n/a
8 P26393_DTP P26393 Glucose-1-phosphate thymidylyltransferase (EC n/a
9 Q97W02_DTP Q97W02 DNA polymerase IV n/a
10 P49902_DTP P49902 Cytosolic purine 5'-nucleotidase n/a
11 O69980_DTP O69980 Transcriptional repressor NrdR n/a
12 P77933_DTP P77933 DNA polymerase (EC n/a
13 Q9NP87_DTP Q9NP87 DNA-directed DNA/RNA polymerase n/a
14 D1CGD0_DTP D1CGD0 CRISPR-associated helicase Cas3 n/a
15 E2GM63_DTP E2GM63 RNA-directed DNA polymerase n/a
16 A0A7U3TBV6_DTP A0A7U3TBV6 N6-succino-2-amino-2'-deoxyadenylate synthase (EC n/a
17 P04585_DTP P04585 Gag-Pol polyprotein (Pr160Gag-Pol) n/a
18 Q96LW4_DTP Q96LW4 DNA-directed primase/polymerase protein n/a
19 Q16854_DTP Q16854 Deoxyguanosine kinase, mitochondrial n/a
20 Q9UNA4_DTP Q9UNA4 DNA polymerase iota n/a
21 Q836G9_DTP Q836G9 HD domain protein n/a
22 P0A5U4_DTP P0A5U4 Protein RecA (Recombinase n/a
23 P06766_DTP P06766 DNA polymerase beta n/a
24 D9N168_DTP D9N168 DNA polymerase I n/a
25 P03366_DTP P03366 Gag-Pol polyprotein (Pr160Gag-Pol) n/a
26 P21189_DTP P21189 DNA polymerase II n/a
27 P06746_DTP P06746 DNA polymerase beta n/a
28 P12493_DTP P12493 Gag polyprotein (Pr55Gag) n/a
29 Q9T0V5_DTP Q9T0V5 Anaerobic ribonucleoside-triphosphate reductase n/a
30 A3XHF9_DTP A3XHF9 ribonucleoside-diphosphate reductase (EC n/a
31 Q9UBT6_DTP Q9UBT6 DNA polymerase kappa n/a
32 Q08698_DTP Q08698 Ribonucleoside-diphosphate reductase 2 n/a
33 Q5F8Z6_DTP Q5F8Z6 Ribonucleoside-diphosphate reductase (EC n/a
34 P00452_DTP P00452 Ribonucleoside-diphosphate reductase 1 n/a
35 Q59560_DTP Q59560 Protein RecA (Recombinase n/a
36 P13569_DTP P13569 Cystic fibrosis transmembrane n/a
37 P09884_DTP P09884 DNA polymerase alpha n/a
38 A0A7I9C3S1_DTP A0A7I9C3S1 deleted n/a
39 P49642_DTP P49642 DNA primase small n/a
40 A0A8I3AZS8_DTP A0A8I3AZS8 DatZ n/a
41 O14727_DTP O14727 Apoptotic protease-activating factor n/a
42 Q56366_DTP Q56366 DNA polymerase (EC n/a
43 Q9UGP5_DTP Q9UGP5 DNA polymerase lambda n/a
44 Q9WYL6_DTP Q9WYL6 Uncharacterized protein n/a
45 P21951_DTP P21951 DNA polymerase epsilon n/a
46 E1C9K5_DTP E1C9K5 DNA polymerase I n/a
47 O33839_DTP O33839 Vitamin B12-dependent ribonucleotide n/a
48 P00973_DTP P00973 2'-5'-oligoadenylate synthase 1 n/a
49 Q9XDH5_DTP Q9XDH5 DNA polymerase III n/a
50 Q9I1X7_DTP Q9I1X7 Multifunctional non-homologous end n/a
51 Q04049_DTP Q04049 DNA polymerase eta n/a
52 Q38087_DTP Q38087 DNA-directed DNA polymerase n/a
53 A3DJ38_DTP A3DJ38 Metallophosphoesterase n/a
54 A0A162Q3J9_DTP A0A162Q3J9 deleted n/a
55 Q9Y253_DTP Q9Y253 DNA polymerase eta n/a
56 A3XHN1_DTP A3XHN1 dGTP triphosphohydrolase n/a
57 Q7KLI1_DTP Q7KLI1 Apoptosome protein Dark n/a
58 R6BY16_DTP R6BY16 deleted n/a
59 P19821_DTP P19821 DNA polymerase I, n/a
60 Q9I4I1_DTP Q9I4I1 Ribonucleoside-diphosphate reductase (EC n/a