Ligand name: N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid
PDB ligand accession: FON
DrugBank: DB03256
PubChem: 135548;5288234;135484651;
ChEMBL: CHEMBL1232801
InChI Key: VVIAGPKUTFNRDU-OLZOCXBDSA-N
SMILES: c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCC2CNC3=C(N2C=O)C(=O)N=C(N3)N

ClassyFire chemical classification:

List of proteins that are targets for DB03256

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P53603_FON P53603 Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) n/a
2 Q9WYA4_FON Q9WYA4 tRNA modification GTPase n/a
3 Q50LF0_FON Q50LF0 Sarcosine oxidase subunit n/a
4 O95954_FON O95954 Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) n/a
5 P77398_FON P77398 Bifunctional polymyxin resistance n/a
6 A5K8L9_FON A5K8L9 glycine hydroxymethyltransferase (EC n/a
7 R4MIX2_FON R4MIX2 dTDP-4-amino-4,6-dideoxyglucose formyltransferase n/a
8 F8RC03_FON F8RC03 Qdtf n/a
9 A0A4P1LYI6_FON A0A4P1LYI6 N-formyltransferase n/a
10 Q8KAS1_FON Q8KAS1 tRNA modification GTPase n/a
11 U3GK13_FON U3GK13 Formyltransferase n/a
12 Q70LM7_FON Q70LM7 Linear gramicidin synthase n/a
13 A8FMJ3_FON A8FMJ3 deleted n/a
14 Q7SIB6_FON Q7SIB6 Serine hydroxymethyltransferase (SHMT) n/a
15 F8WJP6_FON F8WJP6 GDP-perosamine N-formyltransferase (EC n/a
16 C5ZW02_FON C5ZW02 Formyl transferase N-terminal n/a
17 Q8YN91_FON Q8YN91 tRNA modification GTPase n/a