Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
PDB ligand accession: NHE
DrugBank: DB03309
PubChem: 66898;3852474;
ChEMBL: n/a
InChI Key: MKWKNSIESPFAQN-UHFFFAOYSA-N
SMILES: C1CCC(CC1)NCCS(=O)(=O)O

ClassyFire chemical classification:

List of proteins that are targets for DB03309

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P31947_NHE P31947 14-3-3 protein sigma n/a
2 A7ASX7_NHE A7ASX7 Bifunctional dihydrofolate reductase-thymidylate n/a
3 P01889_NHE P01889 HLA class I n/a
4 Q83AY9_NHE Q83AY9 Phosphoribosylglycinamide formyltransferase (EC n/a
5 G3XD33_NHE G3XD33 Heme acquisition protein n/a
6 A5KE01_NHE A5KE01 Adenosine deaminase (EC n/a
7 F4YDQ3_NHE F4YDQ3 Endolysin n/a
8 B2CKP3_NHE B2CKP3 Hemagglutinin/protease regulatory protein n/a
9 B4EUU9_NHE B4EUU9 Sigma factor-binding protein n/a
10 P0C6U8_NHE P0C6U8 Replicase polyprotein 1a n/a
11 O95619_NHE O95619 YEATS domain-containing protein n/a
12 P80244_NHE P80244 ATP-dependent Clp protease n/a
13 Q65EX3_NHE Q65EX3 Cyclo(L-leucyl-L-leucyl) synthase (EC n/a
14 P09622_NHE P09622 Dihydrolipoyl dehydrogenase, mitochondrial n/a
15 Q91MA7_NHE Q91MA7 Hemagglutinin [Cleaved into: n/a
16 P29017_NHE P29017 T-cell surface glycoprotein n/a
17 P78552_NHE P78552 Interleukin-13 receptor subunit n/a
18 Q9X1X7_NHE Q9X1X7 Quinolinate synthase (EC n/a
19 Q5SMG6_NHE Q5SMG6 Glycerate dehydrogenase/glyoxylate reductase n/a
20 Q75DL0_NHE Q75DL0 ABR011Wp n/a
21 Q5M567_NHE Q5M567 Dipeptidase n/a
22 Q5BWX6_NHE Q5BWX6 SJCHGC06286 protein n/a
23 Q54727_NHE Q54727 Sialidase B (EC n/a
24 Q7BSV8_NHE Q7BSV8 Type II secretion n/a
25 Q2YQN9_NHE Q2YQN9 Pyridoxamine 5'-phosphate oxidase n/a
26 Q7A152_NHE Q7A152 Iron-regulated surface determinant n/a
27 P17597_NHE P17597 Acetolactate synthase, chloroplastic n/a
28 P41695_NHE P41695 Spindle assembly checkpoint n/a
29 P15056_NHE P15056 Serine/threonine-protein kinase B-raf n/a
30 O00204_NHE O00204 Sulfotransferase 2B1 (EC n/a
31 P0A6X3_NHE P0A6X3 RNA-binding protein Hfq n/a
32 Q141E8_NHE Q141E8 Pyridoxal kinase PdxY n/a
33 P63746_NHE P63746 Bacterial microcompartment shell n/a
34 Q8X9V6_NHE Q8X9V6 Tellurite methyltransferase n/a
35 P52490_NHE P52490 Ubiquitin-conjugating enzyme E2 n/a
36 Q5EP31_NHE Q5EP31 Hemagglutinin [Cleaved into: n/a
37 P03422_NHE P03422 Phosphoprotein (Protein P) n/a
38 D3PQI8_NHE D3PQI8 V-type ATP synthase n/a
39 W8RJF9_NHE W8RJF9 Fusion glycoprotein F0 n/a
40 Q7Q2T8_NHE Q7Q2T8 Aminopeptidase N (AnAPN1) n/a
41 P22734_NHE P22734 Catechol O-methyltransferase (EC n/a
42 Q9NZ09_NHE Q9NZ09 Ubiquitin-associated protein 1 n/a
43 Q8G0K8_NHE Q8G0K8 deleted n/a
44 P02836_NHE P02836 Segmentation polarity homeobox n/a
45 P06873_NHE P06873 Proteinase K (EC n/a
46 P54300_NHE P54300 Autoinducer 2-binding periplasmic n/a
47 Q1YQT8_NHE Q1YQT8 Short-chain dehydrogenase/reductase SDR n/a
48 Q9NXA8_NHE Q9NXA8 NAD-dependent protein deacylase n/a
49 Q6M5C6_NHE Q6M5C6 deleted n/a
50 A6NHW8_NHE A6NHW8 MSL complex subunit n/a
51 P0A780_NHE P0A780 Transcription antitermination protein n/a
52 Q9HX72_NHE Q9HX72 Acetyltransferase PA3944 (EC n/a
53 P0A7R5_NHE P0A7R5 Small ribosomal subunit n/a
54 H7C785_NHE H7C785 Beta-lactamase (EC 3.5.2.6) n/a
55 Q7WYN3_NHE Q7WYN3 Cellulosomal scaffoldin adaptor n/a
56 P08235_NHE P08235 Mineralocorticoid receptor (MR) n/a
57 O58558_NHE O58558 Putative gamma-glutamylcyclotransferase PH0828 n/a
58 O30077_NHE O30077 Tat proofreading chaperone n/a
59 Q58018_NHE Q58018 Thiamine thiazole synthase n/a
60 B7BGD3_NHE B7BGD3 Regulator of ribonuclease n/a
61 I6L8L5_NHE I6L8L5 TAF6 n/a
62 Q9Y657_NHE Q9Y657 Spindlin-1 (Ovarian cancer-related n/a
63 Q5SLL2_NHE Q5SLL2 Type II toxin-antitoxin n/a
64 K1QRB6_NHE K1QRB6 Natterin-3 n/a
65 G3BK00_NHE G3BK00 TMV resistance protein n/a
66 P00740_NHE P00740 Coagulation factor IX n/a
67 B7T1D9_NHE B7T1D9 Teg14 n/a
68 G9QLG5_NHE G9QLG5 FMN dependent NADH:quinone n/a
69 A0A117IMA6_NHE A0A117IMA6 alpha,alpha-trehalose-phosphate synthase (ADP-forming) n/a
70 Q9V2T0_NHE Q9V2T0 Endoglucanase A n/a
71 Q90922_NHE Q90922 Netrin-1 n/a
72 Q8Z0I2_NHE Q8Z0I2 Alr0114 protein n/a
73 A0A0H2YQR1_NHE A0A0H2YQR1 exo-alpha-sialidase (EC 3.2.1.18) n/a
74 Q9FCQ0_NHE Q9FCQ0 Nitrite reductase (EC n/a
75 C7Q893_NHE C7Q893 Glyoxalase/bleomycin resistance protein/dioxygenase n/a
76 Q9KL03_NHE Q9KL03 Spermidine N(1)-acetyltransferase (SAT) n/a
77 P81180_NHE P81180 Cyanovirin-N (CV-N) n/a
78 A0A0Y5YPU4_NHE A0A0Y5YPU4 deleted n/a
79 Q4K977_NHE Q4K977 Isonitrile hydratase InhA n/a
80 P14902_NHE P14902 Indoleamine 2,3-dioxygenase 1 n/a
81 Q1PST0_NHE Q1PST0 Non-structural protein 1 n/a
82 Q8CPX3_NHE Q8CPX3 deleted n/a
83 A0A2S9PEQ7_NHE A0A2S9PEQ7 deleted n/a
84 P55899_NHE P55899 IgG receptor FcRn n/a
85 P14210_NHE P14210 Hepatocyte growth factor n/a
86 Q13625_NHE Q13625 Apoptosis-stimulating of p53 n/a
87 A1CII2_NHE A1CII2 Phosphoribosylaminoimidazole carboxylase (EC n/a
88 Q5LE92_NHE Q5LE92 Uncharacterized protein n/a
89 Q82US3_NHE Q82US3 Putative AttH n/a
90 P33284_NHE P33284 Hexokinase (EC 2.7.1.1) n/a
91 Q74ZQ8_NHE Q74ZQ8 Suppressor of hydroxyurea n/a
92 A0A160WS51_NHE A0A160WS51 deleted n/a
93 P09979_NHE P09979 Hygromycin-B 7''-O-kinase (EC n/a
94 P9WQ01_NHE P9WQ01 Acetylglutamate kinase (EC n/a
95 P62136_NHE P62136 Serine/threonine-protein phosphatase PP1-alpha n/a
96 Q0P7K8_NHE Q0P7K8 Colibactin self-protection protein n/a
97 A0A290ZVI6_NHE A0A290ZVI6 Toxin n/a
98 B3VMP8_NHE B3VMP8 Pre-neck appendage protein n/a
99 Q5H4I7_NHE Q5H4I7 Malonyl CoA-acyl carrier n/a
100 P03436_NHE P03436 Hemagglutinin [Cleaved into: n/a
101 P03420_NHE P03420 Fusion glycoprotein F0 n/a
102 Q99496_NHE Q99496 E3 ubiquitin-protein ligase n/a
103 P0DTD1_NHE P0DTD1 Replicase polyprotein 1ab n/a
104 P42212_NHE P42212 Green fluorescent protein n/a
105 A0A063XII3_NHE A0A063XII3 Cold shock protein n/a
106 Q9HYZ3_NHE Q9HYZ3 Probable M18 family n/a
107 G8UTM2_NHE G8UTM2 deleted n/a
108 Q9HWJ8_NHE Q9HWJ8 VOC family protein n/a
109 P0A3G3_NHE P0A3G3 Haloalkane dehalogenase (EC n/a
110 B6YTD6_NHE B6YTD6 Glyceraldehyde 3-phosphate phosphatase n/a
111 P61769_NHE P61769 Beta-2-microglobulin [Cleaved into: n/a
112 A0A3B8MYE1_NHE A0A3B8MYE1 Glycine/betaine ABC transporter n/a
113 A5TY84_NHE A5TY84 Serine/threonine-protein kinase PknB n/a
114 A0A076U3E6_NHE A0A076U3E6 deleted n/a
115 A0A0S4TLR1_NHE A0A0S4TLR1 Fucose-binding lectin protein n/a
116 Q8PC69_NHE Q8PC69 protein O-GlcNAc transferase n/a
117 A0A0H3LP08_NHE A0A0H3LP08 Exported protein (Trap n/a
118 Q8U671_NHE Q8U671 Haloalkane dehalogenase (EC n/a
119 B1YH80_NHE B1YH80 SnoaL-like domain-containing protein n/a
120 P54302_NHE P54302 Autoinducer 2 sensor n/a
121 Q9RPL0_NHE Q9RPL0 Endoglucanase (EC 3.2.1.4) n/a
122 Q0ED31_NHE Q0ED31 Envelope glycoprotein gp160 n/a
123 A0A2A6N3G4_NHE A0A2A6N3G4 deleted n/a
124 A0A1I5SVP7_NHE A0A1I5SVP7 Fluorescence recovery protein n/a
125 P50597_NHE P50597 Ribonuclease PH (RNase n/a
126 Q73CY4_NHE Q73CY4 Lipoprotein, putative n/a
127 A0A0F6FBL7_NHE A0A0F6FBL7 deleted n/a
128 Q92769_NHE Q92769 Histone deacetylase 2 n/a