Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
PDB ligand accession: I3P
DrugBank: DB03401
PubChem: 439456
ChEMBL: CHEMBL279107
InChI Key: MMWCIQZXVOZEGG-XJTPDSDZSA-N
SMILES: C1(C(C(C(C(C1OP(=O)(O)O)O)OP(=O)(O)O)OP(=O)(O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for DB03401

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 A0A3G4ZNY6_I3P A0A3G4ZNY6 Kinase n/a
2 Q7WUJ1_I3P Q7WUJ1 Myo-inositol hexaphosphate phosphohydrolase n/a
3 O88339_I3P O88339 Epsin-1 (EPS-15-interacting protein n/a
4 Q9Y6I3_I3P Q9Y6I3 Epsin-1 (EH domain-binding n/a
5 Q01970_I3P Q01970 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase n/a
6 Q01082_I3P Q01082 Spectrin beta chain, n/a
7 P08168_I3P P08168 S-arrestin (48 kDa n/a
8 N9UNA8_I3P N9UNA8 Kinase (EC 2.7.-.-) n/a
9 P35241_I3P P35241 Radixin n/a
10 Q99418_I3P Q99418 Cytohesin-2 (ARF exchange n/a
11 P23677_I3P P23677 Inositol-trisphosphate 3-kinase A n/a
12 Q9VIH7_I3P Q9VIH7 GTPase-activating protein skywalker n/a
13 P29994-2_I3P P29994-2 n/a
14 P03354_I3P P03354 Gag-Pol polyprotein [Cleaved n/a
15 P10688_I3P P10688 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase n/a
16 O00294_I3P O00294 Tubby-related protein 1 n/a
17 P11881_I3P P11881 Inositol 1,4,5-trisphosphate-gated calcium n/a
18 O75129_I3P O75129 Astrotactin-2 n/a
19 P09038_I3P P09038 Fibroblast growth factor n/a
20 Q9DFS3_I3P Q9DFS3 Transient receptor potential n/a
21 P97318_I3P P97318 Disabled homolog 1 n/a
22 Q4W8A1_I3P Q4W8A1 Voltage-sensor containing phosphatase n/a
23 P29994_I3P P29994 Inositol 1,4,5-trisphosphate-gated calcium n/a
24 Q9BRR9_I3P Q9BRR9 Rho GTPase-activating protein n/a
25 Q14573_I3P Q14573 Inositol 1,4,5-trisphosphate-gated calcium inhibitor
26 Q9Y475_I3P Q9Y475 Inositol-trisphosphate 3-kinase C n/a
27 P63034_I3P P63034 Cytohesin-2 (ARF nucleotide-binding n/a
28 Q8NFU5_I3P Q8NFU5 Inositol polyphosphate multikinase n/a
29 P47709_I3P P47709 Rabphilin-3A (Exophilin-1) n/a
30 P10686_I3P P10686 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase n/a
31 P26043_I3P P26043 Radixin (ESP10) n/a
32 P51178_I3P P51178 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase n/a
33 Q62261_I3P Q62261 Spectrin beta chain, n/a