Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: D-MALATE
PDB ligand accession: MLT
DrugBank: DB03499
PubChem: 92824
ChEMBL: CHEMBL225986
InChI Key: BJEPYKJPYRNKOW-UWTATZPHSA-N
SMILES: C(C(C(=O)O)O)C(=O)O

ClassyFire chemical classification:

List of proteins that are targets for DB03499

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q8Y850_MLT Q8Y850 Lmo1068 protein n/a
2 P16692_MLT P16692 Phosphoribosyl 1,2-cyclic phosphate n/a
3 Q9JMB8_MLT Q9JMB8 Contactin-6 (Neural recognition n/a
4 A5I6N2_MLT A5I6N2 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
5 B1MGB2_MLT B1MGB2 Methionine aminopeptidase (MAP) n/a
6 Q9WZQ4_MLT Q9WZQ4 Probable 2-phosphosulfolactate phosphatase n/a
7 D1C982_MLT D1C982 Alpha/beta hydrolase fold n/a
8 D0ZIZ7_MLT D0ZIZ7 deleted n/a
9 Q4JH30_MLT Q4JH30 inorganic diphosphatase (EC n/a
10 A0A088E2H7_MLT A0A088E2H7 Malate dehydrogenase n/a
11 Q9BVJ7_MLT Q9BVJ7 Dual specificity protein n/a
12 P08069_MLT P08069 Insulin-like growth factor n/a
13 Q9CQV8_MLT Q9CQV8 14-3-3 protein beta/alpha n/a
14 Q385Q9_MLT Q385Q9 Transaminase A n/a
15 G3XD33_MLT G3XD33 Heme acquisition protein n/a
16 Q8ZFU4_MLT Q8ZFU4 Dihydroorotase (DHOase) (EC n/a
17 Q8A5V9_MLT Q8A5V9 Beta-phosphoglucomutase n/a
18 Q6N446_MLT Q6N446 Possible TctC subunit n/a
19 Q0C365_MLT Q0C365 Enoyl-CoA hydratase/isomerase family n/a
20 B7KZU4_MLT B7KZU4 MaoC domain protein n/a
21 O75390_MLT O75390 Citrate synthase, mitochondrial n/a
22 C3W5S0_MLT C3W5S0 Polymerase acidic protein n/a
23 Q06124_MLT Q06124 Tyrosine-protein phosphatase non-receptor n/a
24 Q57265_MLT Q57265 Capsule biosynthesis protein n/a
25 Q2TWF5_MLT Q2TWF5 Carbonic anhydrase (EC n/a
26 A9RKG8_MLT A9RKG8 non-specific serine/threonine protein n/a
27 P42212_MLT P42212 Green fluorescent protein n/a
28 P06126_MLT P06126 T-cell surface glycoprotein n/a
29 P0AFV4_MLT P0AFV4 Murein DD-endopeptidase MepS/Murein n/a
30 Q6TV43_MLT Q6TV43 Putative class II n/a
31 P14780_MLT P14780 Matrix metalloproteinase-9 (MMP-9) n/a
32 O81885_MLT O81885 LL-diaminopimelate aminotransferase, chloroplastic n/a
33 Q89F76_MLT Q89F76 ABC transporter substrate-binding n/a
34 Q9KTQ6_MLT Q9KTQ6 Accessory colonization factor n/a
35 B5ZA44_MLT B5ZA44 Guanosine pentaphosphate phosphohydrolase n/a
36 C1K5M2_MLT C1K5M2 Dimethylallylcistransferase CPT1, chloroplastic n/a
37 J3BZS6_MLT J3BZS6 L-lysine 4-hydroxylase (EC n/a
38 Q9H492_MLT Q9H492 Microtubule-associated protein 1 n/a
39 P23368_MLT P23368 NAD-dependent malic enzyme, n/a
40 Q9NZ08_MLT Q9NZ08 Endoplasmic reticulum aminopeptidase n/a
41 Q06121_MLT Q06121 Indole-3-glycerol phosphate synthase n/a
42 P0DTD1_MLT P0DTD1 Replicase polyprotein 1ab n/a
43 A0A229Y1X4_MLT A0A229Y1X4 Thioredoxin reductase (EC n/a
44 O57767_MLT O57767 Quinolinate synthase (QS) n/a
45 Q6PIF6_MLT Q6PIF6 Unconventional myosin-VIIb n/a
46 P30615_MLT P30615 Pyruvate kinase 1 n/a
47 Q9I6R5_MLT Q9I6R5 Probable dihydrodipicolinate synthetase n/a
48 O75044_MLT O75044 SLIT-ROBO Rho GTPase-activating n/a
49 I6XG39_MLT I6XG39 Genome polyprotein n/a
50 A0A8X6EGU0_MLT A0A8X6EGU0 CirpA1 n/a
51 A0A023GPI5_MLT A0A023GPI5 CBIX n/a
52 W8VGR4_MLT W8VGR4 3-oxoacyl-[acyl-carrier protein] reductase n/a
53 P38636_MLT P38636 Copper chaperone ATX1 n/a
54 Q2T095_MLT Q2T095 Pantothenate synthetase (PS) n/a
55 Q8DDT3_MLT Q8DDT3 deleted n/a
56 G0S6M7_MLT G0S6M7 Probable vacuolar protein n/a
57 P93114_MLT P93114 Jacalin-related lectin Calsepa n/a
58 O75874_MLT O75874 Isocitrate dehydrogenase [NADP] n/a
59 Q8ZNF9_MLT Q8ZNF9 L-rhamnonate dehydratase (RhamD) n/a
60 Q05909_MLT Q05909 Receptor-type tyrosine-protein phosphatase n/a
61 Q9CJC1_MLT Q9CJC1 Dienelactone hydrolase domain-containing n/a
62 Q56905_MLT Q56905 dTDP-4-dehydrorhamnose reductase (EC n/a
63 Q6G5B4_MLT Q6G5B4 deleted n/a
64 O53611_MLT O53611 Isocitrate dehydrogenase [NADP] n/a
65 S8GQK2_MLT S8GQK2 ribose-5-phosphate isomerase (EC n/a
66 P23007_MLT P23007 Citrate synthase, mitochondrial n/a
67 P74645_MLT P74645 Circadian clock oscillator n/a
68 P96228_MLT P96228 Nucleoid-associated protein EspR n/a
69 D5CXR1_MLT D5CXR1 deleted n/a
70 C5XC49_MLT C5XC49 cinnamyl-alcohol dehydrogenase (EC n/a
71 P40926_MLT P40926 Malate dehydrogenase, mitochondrial n/a
72 H2VFG5_MLT H2VFG5 N-acetylneuraminate synthase (EC n/a
73 Q10714_MLT Q10714 Angiotensin-converting enzyme (EC n/a
74 A0A0M3KKY6_MLT A0A0M3KKY6 Esterase (EC 3.1.1.1) n/a
75 Q81ST7_MLT Q81ST7 N-acetyl-alpha-D-glucosaminyl L-malate synthase n/a
76 P55211_MLT P55211 Caspase-9 (CASP-9) (EC n/a
77 Q84KR7_MLT Q84KR7 phosphoenolpyruvate carboxylase (EC n/a
78 A3PQL6_MLT A3PQL6 deleted n/a
79 K5B7Z4_MLT K5B7Z4 Glucosyl-3-phosphoglycerate synthase (EC n/a
80 Q8N465_MLT Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial n/a
81 Q81ST4_MLT Q81ST4 EfeO-type cupredoxin-like domain-containing n/a
82 P22523_MLT P22523 Chromosome partition protein n/a
83 P0A786_MLT P0A786 Aspartate carbamoyltransferase catalytic n/a
84 Q5NFG1_MLT Q5NFG1 Macrophage growth locus, n/a
85 Q5S3G7_MLT Q5S3G7 Fluorescent protein plum n/a
86 G0LCA3_MLT G0LCA3 Alginate lyase, family n/a
87 A0A2H4T920_MLT A0A2H4T920 Taurine catabolism dioxygenase n/a
88 P9WFX9_MLT P9WFX9 Tryptophan synthase beta n/a
89 Q0P8W7_MLT Q0P8W7 Biotin carboxylase (EC n/a
90 Q6L8Q5_MLT Q6L8Q5 aminodeoxychorismate synthase (EC n/a
91 P32021_MLT P32021 2-oxoglutarate-dependent ethylene/succinate-forming enzyme n/a
92 A5U4M0_MLT A5U4M0 Anthranilate phosphoribosyltransferase (EC n/a
93 G3I8R9_MLT G3I8R9 Endoplasmic reticulum chaperone n/a
94 O43175_MLT O43175 D-3-phosphoglycerate dehydrogenase (3-PGDH) n/a
95 Q3JRA0_MLT Q3JRA0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
96 P05042_MLT P05042 Fumarate hydratase class n/a
97 P59310_MLT P59310 N-acetyl-gamma-glutamyl-phosphate reductase (AGPR) n/a
98 P0A5J4_MLT P0A5J4 Malate synthase G n/a
99 P65306_MLT P65306 Putative phthiocerol dimycocerosate n/a
100 P78504_MLT P78504 Protein jagged-1 (Jagged1) n/a
101 Q13554_MLT Q13554 Calcium/calmodulin-dependent protein kinase n/a
102 Q58261_MLT Q58261 Tetrahydromethanopterin S-methyltransferase subunit n/a
103 B2UCA8_MLT B2UCA8 D-galactonate dehydratase (GalD) n/a
104 Q92SA6_MLT Q92SA6 ADP-polyphosphate phosphotransferase 1 n/a
105 Q93NW7_MLT Q93NW7 AmphB n/a
106 Q96C55_MLT Q96C55 Zinc finger protein n/a
107 P24305_MLT P24305 Outer membrane porin n/a
108 Q88QV5_MLT Q88QV5 Coenzyme PQQ synthesis n/a
109 Q1RQU8_MLT Q1RQU8 Putative hydrolase n/a
110 Q70I53_MLT Q70I53 Histone deacetylase-like amidohydrolase n/a
111 B4EEF2_MLT B4EEF2 Dihydrolipoyl dehydrogenase (EC n/a
112 P02689_MLT P02689 Myelin P2 protein n/a
113 P27707_MLT P27707 Deoxycytidine kinase (dCK) n/a
114 P64767_MLT P64767 Intracellular chorismate mutase n/a
115 A0A0B6NVJ4_MLT A0A0B6NVJ4 deleted n/a