Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: N-acetyl-alpha-neuraminic acid
PDB ligand accession: SIA
DrugBank: DB03721
PubChem: 444885
ChEMBL: CHEMBL1234621
InChI Key: SQVRNKJHWKZAKO-YRMXFSIDSA-N
SMILES: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for DB03721

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P03472_SIA P03472 Neuraminidase (EC 3.2.1.18) n/a
2 P03089_SIA P03089 Major capsid protein n/a
3 Q59310_SIA Q59310 exo-alpha-sialidase (EC 3.2.1.18) n/a
4 P06820_SIA P06820 Neuraminidase (EC 3.2.1.18) n/a
5 A0A0J9X248_SIA A0A0J9X248 Hemagglutinin n/a
6 Q9UKJ0_SIA Q9UKJ0 Paired immunoglobulin-like type n/a
7 O15389_SIA O15389 Sialic acid-binding Ig-like n/a
8 R4NN21_SIA R4NN21 Hemagglutinin [Cleaved into: n/a
9 V5IRV0_SIA V5IRV0 Hemagglutinin n/a
10 P37060_SIA P37060 Sialidase (EC 3.2.1.18) n/a
11 P10845_SIA P10845 Botulinum neurotoxin type n/a
12 I2D7A8_SIA I2D7A8 Hemagglutinin [Cleaved into: n/a
13 Q20UH7_SIA Q20UH7 Neuraminidase (EC 3.2.1.18) n/a
14 Q65613_SIA Q65613 Capsid protein VP1 n/a
15 E2ESL7_SIA E2ESL7 Capsid protein VP1 n/a
16 A0A0J9X246_SIA A0A0J9X246 Hemagglutinin n/a
17 B2DJD9_SIA B2DJD9 deleted n/a
18 P05451_SIA P05451 Lithostathine-1-alpha (Islet cells n/a
19 A0A716TY65_SIA A0A716TY65 Subtilase cytotoxin subunit n/a
20 H6W8F2_SIA H6W8F2 Heat-labile enterotoxin IIA, n/a
21 E1CIQ3_SIA E1CIQ3 Fiber n/a
22 Q9WCE0_SIA Q9WCE0 Hemagglutinin [Cleaved into: n/a
23 Q97Q99_SIA Q97Q99 deleted n/a
24 Q7MX62_SIA Q7MX62 exo-alpha-sialidase (EC 3.2.1.18) n/a
25 A0A0J9X252_SIA A0A0J9X252 Hemagglutinin n/a
26 R4UMH0_SIA R4UMH0 Capsid protein VP1 n/a
27 Q82847_SIA Q82847 Hemagglutinin n/a
28 Q309D1_SIA Q309D1 Lectin PVL n/a
29 P16109_SIA P16109 P-selectin (CD62 antigen-like inhibitor
30 C0JPK1_SIA C0JPK1 VP1 n/a
31 Q9UK77_SIA Q9UK77 Liver carboxylesterase 1 n/a
32 A0A0H2UQE4_SIA A0A0H2UQE4 exo-alpha-sialidase (EC 3.2.1.18) n/a
33 P16581_SIA P16581 E-selectin (CD62 antigen-like inhibitor
34 A0A0J9X268_SIA A0A0J9X268 Hemagglutinin n/a
35 A0A140AYW5_SIA A0A140AYW5 Spike glycoprotein (S n/a
36 R4NFR6_SIA R4NFR6 Neuraminidase (EC 3.2.1.18) n/a
37 P32884_SIA P32884 Hemagglutinin-neuraminidase (EC 3.2.1.18) n/a
38 C3PR70_SIA C3PR70 Hemagglutinin [Cleaved into: n/a
39 P03437_SIA P03437 Hemagglutinin [Cleaved into: n/a
40 Q9BZZ2_SIA Q9BZZ2 Sialoadhesin (Sialic acid-binding n/a
41 A3KF09_SIA A3KF09 Hemagglutinin [Cleaved into: n/a
42 A0A2I7YV81_SIA A0A2I7YV81 Hemagglutinin [Cleaved into: n/a
43 P06276_SIA P06276 Cholinesterase (EC 3.1.1.8) n/a
44 P03528_SIA P03528 Outer capsid protein n/a
45 K7N5N3_SIA K7N5N3 Neuraminidase (EC 3.2.1.18) n/a
46 Q8Z6A3_SIA Q8Z6A3 Pertussis-like toxin subunit n/a
47 Q6XV27_SIA Q6XV27 Neuraminidase (EC 3.2.1.18) n/a
48 A5Z226_SIA A5Z226 Hemagglutinin [Cleaved into: n/a
49 A0A0A7HR51_SIA A0A0A7HR51 Hemagglutinin n/a
50 K0BRG7_SIA K0BRG7 Spike glycoprotein (S n/a
51 A0A0H2YQR1_SIA A0A0H2YQR1 exo-alpha-sialidase (EC 3.2.1.18) n/a
52 P62576_SIA P62576 Sialidase A (EC n/a
53 Q91MA7_SIA Q91MA7 Hemagglutinin [Cleaved into: n/a
54 P02743_SIA P02743 Serum amyloid P-component n/a
55 Q2TLC1_SIA Q2TLC1 deleted n/a
56 A8W891_SIA A8W891 Hemagglutinin n/a
57 E5RWD1_SIA E5RWD1 Fiber protein n/a
58 P42216_SIA P42216 3-deoxy-manno-octulosonate cytidylyltransferase (EC n/a
59 P11226_SIA P11226 Mannose-binding protein C n/a
60 A0A0E3ZCF3_SIA A0A0E3ZCF3 Capsid protein VP1 n/a
61 Q9WBP8_SIA Q9WBP8 Capsid protein n/a
62 O44049_SIA O44049 Sialidase (EC 3.2.1.18) n/a
63 P25311_SIA P25311 Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein) n/a
64 Q9KWR3_SIA Q9KWR3 Streptococcal hemagglutinin (Hs n/a
65 P20138_SIA P20138 Myeloid cell surface n/a
66 Q8AZ87_SIA Q8AZ87 Neuraminidase (EC 3.2.1.18) n/a
67 Q80S15_SIA Q80S15 Fiber protein n/a
68 C3W5S1_SIA C3W5S1 Hemagglutinin [Cleaved into: n/a
69 A4GYF9_SIA A4GYF9 Hemagglutinin n/a
70 Q64823_SIA Q64823 Fiber n/a
71 P18640_SIA P18640 Botulinum neurotoxin type n/a
72 R9U684_SIA R9U684 Hemagglutinin [Cleaved into: n/a
73 Q8T9N3_SIA Q8T9N3 BAEBL protein (Erythrocyte n/a
74 Q9LBR1_SIA Q9LBR1 Neurotoxin n/a
75 P90498_SIA P90498 Capsid protein VP1 n/a
76 Q6VMK1_SIA Q6VMK1 Hemagglutinin [Cleaved into: n/a
77 Q8CJ91_SIA Q8CJ91 CD209 antigen-like protein n/a
78 A4ZKM1_SIA A4ZKM1 Fiber n/a
79 A5JGM8_SIA A5JGM8 Neurotoxin (EC 3.4.24.69) n/a
80 P43529_SIA P43529 Heat-labile enterotoxin IIB, n/a
81 P23141_SIA P23141 Liver carboxylesterase 1 inhibitor
82 Q6DQ33_SIA Q6DQ33 Hemagglutinin n/a
83 V9VEF3_SIA V9VEF3 Genome polyprotein [Cleaved n/a
84 M4T5D3_SIA M4T5D3 Capsid protein VP1 n/a
85 Q62230_SIA Q62230 Sialoadhesin (Sheep erythrocyte n/a
86 Q65914_SIA Q65914 Fiber protein (SPIKE) n/a
87 A0MK70_SIA A0MK70 Fiber-1 n/a
88 Q67326_SIA Q67326 Hemagglutinin [Cleaved into: n/a
89 P27907_SIA P27907 Neuraminidase (EC 3.2.1.18) n/a
90 Q6DQ34_SIA Q6DQ34 Hemagglutinin n/a
91 Q404H3_SIA Q404H3 ArtB protein n/a
92 A0A059T4A1_SIA A0A059T4A1 Hemagglutinin [Cleaved into: n/a
93 Q75WT9_SIA Q75WT9 Ricin B-related lectin n/a
94 Q50341_SIA Q50341 Mgp-operon protein 3 n/a
95 A0A059VBQ9_SIA A0A059VBQ9 Hemagglutinin [Cleaved into: n/a
96 Q0TTQ4_SIA Q0TTQ4 deleted n/a
97 Q67333_SIA Q67333 Hemagglutinin [Cleaved into: n/a
98 P0DTC2_SIA P0DTC2 Spike glycoprotein (S n/a