Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
PDB ligand accession: GCP
DrugBank: DB03725
PubChem: 93082;5280942;135398731;
ChEMBL: n/a
InChI Key: PHBDHXOBFUBCJD-KQYNXXCUSA-N
SMILES: c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OP(=O)(CP(=O)(O)O)O)O)O)N=C(NC2=O)N

ClassyFire chemical classification:

List of proteins that are targets for DB03725

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 O80842_GCP O80842 Cell division protein n/a
2 Q6CIX3_GCP Q6CIX3 KLLA0F23265p n/a
3 Q96RP9_GCP Q96RP9 Elongation factor G, n/a
4 B1XFI4_GCP B1XFI4 Peptide chain release n/a
5 P32481_GCP P32481 Eukaryotic translation initiation n/a
6 P39730_GCP P39730 Eukaryotic translation initiation n/a
7 P53590_GCP P53590 Succinate--CoA ligase [GDP-forming] n/a
8 Q96NW4_GCP Q96NW4 Ankyrin repeat domain-containing n/a
9 A0A8H4BUS5_GCP A0A8H4BUS5 deleted n/a
10 B7MHF0_GCP B7MHF0 Large ribosomal subunit n/a
11 A0A0E3JTX3_GCP A0A0E3JTX3 Translation initiation factor n/a
12 A0A062V290_GCP A0A062V290 Elongation factor 2 n/a
13 Q5SKA7_GCP Q5SKA7 Elongation factor 4 n/a
14 Q5SLQ1_GCP Q5SLQ1 Large ribosomal subunit n/a
15 Q9UQ13_GCP Q9UQ13 Leucine-rich repeat protein n/a
16 O07347_GCP O07347 Signal recognition particle n/a
17 Q9BT17_GCP Q9BT17 Mitochondrial ribosome-associated GTPase n/a
18 B7LEM0_GCP B7LEM0 Peptide chain release n/a
19 P57772_GCP P57772 Selenocysteine-specific elongation factor n/a
20 O00429_GCP O00429 Dynamin-1-like protein (EC n/a
21 A0A6A5Q017_GCP A0A6A5Q017 deleted n/a
22 P50743_GCP P50743 GTPase Der (GTP-binding n/a
23 P49411_GCP P49411 Elongation factor Tu, n/a
24 O14807_GCP O14807 Ras-related protein M-Ras n/a
25 Q9HV55_GCP Q9HV55 Translation initiation factor n/a
26 P01112_GCP P01112 GTPase HRas (EC n/a
27 P47122_GCP P47122 GPN-loop GTPase 1 n/a
28 Q8EG04_GCP Q8EG04 Ras-like GTPase YcjX n/a
29 P83749_GCP P83749 Signal recognition particle n/a
30 Q13637_GCP Q13637 Ras-related protein Rab-32 n/a
31 O59521_GCP O59521 Elongation factor 2 n/a
32 H4UQ46_GCP H4UQ46 deleted n/a
33 Q980A5_GCP Q980A5 Translation initiation factor n/a
34 P60339_GCP P60339 Elongation factor Tu-B n/a
35 Q5SHN5_GCP Q5SHN5 Elongation factor G n/a
36 Q8IXI2_GCP Q8IXI2 Mitochondrial Rho GTPase n/a
37 P35558_GCP P35558 Phosphoenolpyruvate carboxykinase, cytosolic n/a
38 U9XYS4_GCP U9XYS4 deleted n/a
39 P63810_GCP P63810 Pantothenate kinase (EC n/a
40 P60953_GCP P60953 Cell division control n/a
41 P15170_GCP P15170 Eukaryotic peptide chain n/a
42 P0A3B2_GCP P0A3B2 Large ribosomal subunit n/a
43 P01116_GCP P01116 GTPase KRas (EC n/a
44 P69441_GCP P69441 Adenylate kinase (AK) n/a
45 G1TNM3_GCP G1TNM3 Small ribosomal subunit n/a
46 P0CE47_GCP P0CE47 Elongation factor Tu n/a
47 W7R097_GCP W7R097 deleted n/a
48 P37107_GCP P37107 Signal recognition particle n/a
49 Q47810_GCP Q47810 Tetracycline resistance protein n/a
50 P0A0C1_GCP P0A0C1 Bifunctional AAC/APH [Includes: n/a
51 P20591_GCP P20591 Interferon-induced GTP-binding protein n/a
52 P01116-2_GCP P01116-2 n/a
53 Q969S9_GCP Q969S9 Ribosome-releasing factor 2, n/a
54 P33650_GCP P33650 Fe(2+) transporter FeoB n/a
55 O19069_GCP O19069 Succinate--CoA ligase [ADP/GDP-forming] n/a
56 P09064_GCP P09064 Eukaryotic translation initiation n/a
57 P0AGD7_GCP P0AGD7 Signal recognition particle n/a
58 P63000_GCP P63000 Ras-related C3 botulinum n/a
59 P0A031_GCP P0A031 Cell division protein n/a
60 C5AP93_GCP C5AP93 Methylmalonyl-CoA mutase accessory n/a
61 P60763_GCP P60763 Ras-related C3 botulinum n/a
62 P0A6M8_GCP P0A6M8 Elongation factor G n/a
63 Q8KAS1_GCP Q8KAS1 tRNA modification GTPase n/a
64 P0A7D4_GCP P0A7D4 Adenylosuccinate synthetase (AMPSase) n/a
65 Q9Y450_GCP Q9Y450 HBS1-like protein (EC n/a
66 G0SFF0_GCP G0SFF0 Putative sorting protein n/a
67 Q05193_GCP Q05193 Dynamin-1 (EC 3.6.5.5) n/a
68 P32324_GCP P32324 Elongation factor 2 n/a
69 E1AQY1_GCP E1AQY1 Adenylate cyclase n/a
70 P0A7I4_GCP P0A7I4 Peptide chain release n/a
71 P13551_GCP P13551 Elongation factor G n/a
72 P10121_GCP P10121 Signal recognition particle n/a