Ligand name: ROLIPRAM
PDB ligand accession: ROL
DrugBank: DB04149
PubChem: 448055
ChEMBL: CHEMBL430893
InChI Key: HJORMJIFDVBMOB-LBPRGKRZSA-N
SMILES: COc1ccc(cc1OC2CCCC2)C3CC(=O)NC3

ClassyFire chemical classification:

List of proteins that are targets for DB04149

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q08499_ROL Q08499 3',5'-cyclic-AMP phosphodiesterase 4D n/a IC50(nM) = 231.0
2 Q07343_ROL Q07343 3',5'-cyclic-AMP phosphodiesterase 4B inhibitor IC50(nM) = 39.81
3 A4TVL0_ROL A4TVL0 Cereblon isoform 4 n/a