Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: INOSINIC ACID
PDB ligand accession: IMP
DrugBank: DB04566
PubChem: 8582;5280323;135398640;
ChEMBL: CHEMBL1207374
InChI Key: GRSZFWQUAKGDAV-KQYNXXCUSA-N
SMILES: c1nc2c(n1C3C(C(C(O3)COP(=O)(O)O)O)O)N=CNC2=O

ClassyFire chemical classification:

List of proteins that are targets for DB04566

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 A0A0M3KL00_IMP A0A0M3KL00 Phosphomethylpyrimidine kinase n/a
2 P20839-5_IMP P20839-5 n/a
3 Q5CPK7_IMP Q5CPK7 Inosine-5-monophosphate dehydrogenase (EC n/a
4 P9WKI7_IMP P9WKI7 Inosine-5'-monophosphate dehydrogenase (IMP n/a
5 Q9WY06_IMP Q9WY06 dITP/XTP pyrophosphatase (EC n/a
6 Q96DE0_IMP Q96DE0 U8 snoRNA-decapping enzyme n/a
7 A0A127ELD1_IMP A0A127ELD1 Inosine-5'-monophosphate dehydrogenase (IMP n/a
8 P11217_IMP P11217 Glycogen phosphorylase, muscle inhibitor
9 Q0TN42_IMP Q0TN42 deleted n/a
10 J9VI09_IMP J9VI09 Adenylosuccinate synthetase (AMPSase) n/a
11 Q5SLS1_IMP Q5SLS1 Adenylosuccinate synthetase (AMPSase) n/a
12 Q9KTW3_IMP Q9KTW3 Inosine-5'-monophosphate dehydrogenase (IMP n/a
13 Q07010_IMP Q07010 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) n/a
14 O58187_IMP O58187 Adenylosuccinate synthetase (AMPSase) n/a
15 P12269_IMP P12269 Inosine-5'-monophosphate dehydrogenase 2 n/a
16 P0ADG7_IMP P0ADG7 Inosine-5'-monophosphate dehydrogenase (IMP n/a
17 P0A7D4_IMP P0A7D4 Adenylosuccinate synthetase (AMPSase) n/a
18 P07741_IMP P07741 Adenine phosphoribosyltransferase (APRT) n/a
19 Q99QC1_IMP Q99QC1 Beta-lactamase CMY-10 (EC n/a
20 A0A069Q6I8_IMP A0A069Q6I8 Inosine-5'-monophosphate dehydrogenase (IMP n/a
21 E3P6S0_IMP E3P6S0 Inosine-5'-monophosphate dehydrogenase (IMP n/a
22 Q926Y9_IMP Q926Y9 Inosine-5'-monophosphate dehydrogenase (IMP n/a
23 P12268_IMP P12268 Inosine-5'-monophosphate dehydrogenase 2 inhibitor
24 O27099_IMP O27099 IMP cyclohydrolase (EC n/a
25 A0A6H3A7R4_IMP A0A6H3A7R4 deleted n/a
26 P00489_IMP P00489 Glycogen phosphorylase, muscle n/a
27 Q756Z6_IMP Q756Z6 Inosine-5'-monophosphate dehydrogenase (IMP n/a
28 P49773_IMP P49773 Adenosine 5'-monophosphoramidase HINT1 n/a
29 Q92871_IMP Q92871 Phosphomannomutase 1 (PMM n/a
30 Q9BY32_IMP Q9BY32 Inosine triphosphate pyrophosphatase n/a
31 P31947_IMP P31947 14-3-3 protein sigma n/a
32 A0A100XBM0_IMP A0A100XBM0 Inosine-5'-monophosphate dehydrogenase (IMP n/a
33 Q27796_IMP Q27796 Hypoxanthine phosphoribosyltransferase (EC n/a
34 P56137_IMP P56137 Adenylosuccinate synthetase (AMPSase) n/a
35 G7CNL4_IMP G7CNL4 Inosine-5'-monophosphate dehydrogenase (IMP n/a
36 Q81W29_IMP Q81W29 Inosine-5'-monophosphate dehydrogenase (IMP n/a
37 Q9P2T1_IMP Q9P2T1 GMP reductase 2 n/a
38 A0A1B3XFT6_IMP A0A1B3XFT6 deleted n/a
39 P00968_IMP P00968 Carbamoyl phosphate synthase n/a
40 P28650_IMP P28650 Adenylosuccinate synthetase isozyme n/a
41 Q0P9J4_IMP Q0P9J4 Inosine-5'-monophosphate dehydrogenase (IMP n/a
42 P50097_IMP P50097 Inosine-5'-monophosphate dehydrogenase (IMP n/a
43 P20839_IMP P20839 Inosine-5'-monophosphate dehydrogenase 1 inhibitor
44 P49902_IMP P49902 Cytosolic purine 5'-nucleotidase n/a
45 Q8R7L0_IMP Q8R7L0 Hypoxanthine phosphoribosyltransferase (EC n/a
46 G4LWQ2_IMP G4LWQ2 deleted n/a
47 Q8LPL7_IMP Q8LPL7 N6-mAMP deaminase (AtMAPDA) n/a
48 Q26997_IMP Q26997 Hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGPRT) n/a
49 O59580_IMP O59580 dITP/XTP pyrophosphatase (EC n/a
50 A0A0H2YRZ7_IMP A0A0H2YRZ7 Inosine-5'-monophosphate dehydrogenase (IMP n/a
51 Q8N142_IMP Q8N142 Adenylosuccinate synthetase isozyme n/a
52 P52061_IMP P52061 dITP/XTP pyrophosphatase (EC n/a
53 Q8T6T2_IMP Q8T6T2 Inosine-5'-monophosphate dehydrogenase (IMP n/a
54 Q38CA1_IMP Q38CA1 Hypoxanthine-guanine phosphoribosyltransferase, putative n/a
55 P21589_IMP P21589 5'-nucleotidase (5'-NT) (EC n/a
56 P0C0H6_IMP P0C0H6 Inosine-5'-monophosphate dehydrogenase (IMP n/a
57 P0A9M2_IMP P0A9M2 Hypoxanthine phosphoribosyltransferase (HPRT) n/a
58 P12283_IMP P12283 Adenylosuccinate synthetase (AMPSase) n/a
59 Q9HXM5_IMP Q9HXM5 Inosine-5'-monophosphate dehydrogenase (IMP n/a
60 Q5SLS3_IMP Q5SLS3 Hypoxanthine phosphoribosyltransferase (EC n/a
61 P61823_IMP P61823 Ribonuclease pancreatic (EC n/a
62 G3FFN6_IMP G3FFN6 N6-succino-2-amino-2'-deoxyadenylate synthase (EC n/a
63 Q8YAJ3_IMP Q8YAJ3 Lmo0132 protein n/a