Ligand name: Iloperidone
PDB ligand accession: n/a
DrugBank: DB04946
InChI Key:
SMILES: COC1=C(OCCCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C=CC(=C1)C(C)=O

List of proteins that are targets for DB04946

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P18825_DB04946	P18825	Alpha-2C adrenergic receptor	antagonist	Ki(nM) = 16.2
2	P35462_DB04946	P35462	D(3) dopamine receptor	antagonist	Ki(nM) = 7.1
3	P34969_DB04946	P34969	5-hydroxytryptamine receptor 7	antagonist	Ki(nM) = 112.0
4	P50406_DB04946	P50406	5-hydroxytryptamine receptor 6	antagonist	Ki(nM) = 63.1
5	P14416_DB04946	P14416	D(2) dopamine receptor	antagonist	Ki(nM) = 0.35 IC50(nM) = 110.0
6	P08908_DB04946	P08908	5-hydroxytryptamine receptor 1A	antagonist	Ki(nM) = 33.0
7	P35367_DB04946	P35367	Histamine H1 receptor	antagonist	Ki(nM) = 12.3
8	P21728_DB04946	P21728	D(1A) dopamine receptor	antagonist	Ki(nM) = 216.0
9	P28223_DB04946	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 0.12
10	P21917_DB04946	P21917	D(4) dopamine receptor	antagonist	Ki(nM) = 2.5
11	P35348_DB04946	P35348	Alpha-1A adrenergic receptor	antagonist	Ki(nM) = 0.31