Ligand name: 2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
PDB ligand accession: AVL
DrugBank: DB05266
PubChem: 3671
ChEMBL: CHEMBL19449
InChI Key: ZJVFLBOZORBYFE-UHFFFAOYSA-N
SMILES: CC(C)c1c(c2ccccn2n1)C(=O)C(C)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyrazolopyridines
      • Subclass: None

List of proteins that are targets for DB05266

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P27815_AVL	P27815	3',5'-cyclic-AMP phosphodiesterase 4A	inhibitor	IC50(nM) = 54.0 EC50(nM) = 900.0
2	Q08493_AVL	Q08493	3',5'-cyclic-AMP phosphodiesterase 4C	inhibitor	IC50(nM) = 239.0
3	Q07343_AVL	Q07343	3',5'-cyclic-AMP phosphodiesterase 4B	inhibitor	IC50(nM) = 65.0
4	P14174_AVL	P14174	Macrophage migration inhibitory	n/a	Ki(nM) = 30900.0 Kd(nM) = 1400.0
5	Q08499_AVL	Q08499	3',5'-cyclic-AMP phosphodiesterase 4D	inhibitor	IC50(nM) = 166.0
6	Q14432_AVL	Q14432	cGMP-inhibited 3',5'-cyclic phosphodiesterase	inhibitor	IC50(nM) = 299000.0