Ligand name: Asenapine
PDB ligand accession: n/a
DrugBank: DB06216
InChI Key:
SMILES: CN1CC2C(C1)C1=C(OC3=CC=C(Cl)C=C23)C=CC=C1

List of proteins that are targets for DB06216

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P18825_DB06216	P18825	Alpha-2C adrenergic receptor	antagonist	Ki(nM) = 13.0
2	P14416_DB06216	P14416	D(2) dopamine receptor	antagonist	Ki(nM) = 1.87
3	P28335_DB06216	P28335	5-hydroxytryptamine receptor 2C	antagonist	Ki(nM) = 0.2
4	P21728_DB06216	P21728	D(1A) dopamine receptor	antagonist
5	P41595_DB06216	P41595	5-hydroxytryptamine receptor 2B	antagonist	Ki(nM) = 0.21
6	P35348_DB06216	P35348	Alpha-1A adrenergic receptor	antagonist	Ki(nM) = 1.1
7	P18089_DB06216	P18089	Alpha-2B adrenergic receptor	antagonist	Ki(nM) = 0.49
8	P28222_DB06216	P28222	5-hydroxytryptamine receptor 1B	antagonist	Ki(nM) = 3.9
9	P21917_DB06216	P21917	D(4) dopamine receptor	antagonist	Ki(nM) = 3.8
10	P08913_DB06216	P08913	Alpha-2A adrenergic receptor	antagonist	Ki(nM) = 6.5
11	P07550_DB06216	P07550	Beta-2 adrenergic receptor	antagonist	Ki(nM) = 5000.0
12	P34969_DB06216	P34969	5-hydroxytryptamine receptor 7	antagonist
13	P35462_DB06216	P35462	D(3) dopamine receptor	antagonist	Ki(nM) = 1.8
14	P28223_DB06216	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 0.26
15	P35367_DB06216	P35367	Histamine H1 receptor	antagonist	Ki(nM) = 0.16
16	P08588_DB06216	P08588	Beta-1 adrenergic receptor	antagonist	Ki(nM) = 5000.0
17	P47898_DB06216	P47898	5-hydroxytryptamine receptor 5A	antagonist
18	P08908_DB06216	P08908	5-hydroxytryptamine receptor 1A	antagonist	Ki(nM) = 10.0
19	P25021_DB06216	P25021	Histamine H2 receptor	antagonist
20	P50406_DB06216	P50406	5-hydroxytryptamine receptor 6	antagonist