PDB ligand accession: DJK
DrugBank: DB07662
PubChem:
ChEMBL:
InChI Key: HTUBKQUPEREOGA-UHFFFAOYSA-N
SMILES: C=CC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br
ClassyFire chemical classification:
- Kingdom: Organic compounds
- Superclass: Organoheterocyclic compounds
- Class: Diazanaphthalenes
- Subclass: Benzodiazines
- Class: Diazanaphthalenes
- Superclass: Organoheterocyclic compounds
# | DrugDomain Data | UniProt Accession | Protein name | Drug Action | Affinity data |
---|---|---|---|---|---|
1 | P00533_DJK | P00533 | Epidermal growth factor | inhibitor | IC50(nM) = 0.08 |
2 | P12931_DJK | P12931 | Proto-oncogene tyrosine-protein kinase | n/a | IC50(nM) = 27000.0 |
3 | P00523_DJK | P00523 | Proto-oncogene tyrosine-protein kinase | n/a | IC50(nM) = 340.0 |