Ligand name: TRICLOSAN
PDB ligand accession: TCL
DrugBank: DB08604
PubChem: 5564
ChEMBL: CHEMBL849
InChI Key: XEFQLINVKFYRCS-UHFFFAOYSA-N
SMILES: c1cc(c(cc1Cl)O)Oc2ccc(cc2Cl)Cl

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Diphenylethers

List of proteins that are targets for DB08604

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P80030_TCL	P80030	Enoyl-[acyl-carrier-protein] reductase [NADH],	n/a
2	A0A069B9A4_TCL	A0A069B9A4	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
3	Q5SLI9_TCL	Q5SLI9	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
4	Q9BH77_TCL	Q9BH77	Enoyl-ACP reductase (Enoyl-acyl	n/a
5	P0A5Y6_TCL	P0A5Y6	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
6	P29132_TCL	P29132	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
7	Q6TEI5_TCL	Q6TEI5	Enoyl-acyl carrier protein	n/a
8	Q6GI75_TCL	Q6GI75	Enoyl-[acyl-carrier-protein] reductase [NADPH]	n/a	Ki(nM) = 0.05 IC50(nM) = 59.0
9	O24990_TCL	O24990	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
10	P10275_TCL	P10275	Androgen receptor (Dihydrotestosterone	n/a
11	Q9ZFE4_TCL	Q9ZFE4	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
12	P49327_TCL	P49327	Fatty acid synthase	n/a
13	Q8KLP4_TCL	Q8KLP4	Repressor	n/a
14	Q5NGQ3_TCL	Q5NGQ3	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
15	Q6UCJ9_TCL	Q6UCJ9	Enoyl-acyl carrier reductase	n/a
16	P71079_TCL	P71079	Enoyl-[acyl-carrier-protein] reductase [NADPH]	n/a
17	A0A2J1CZK4_TCL	A0A2J1CZK4	deleted	n/a
18	P37231_TCL	P37231	Peroxisome proliferator-activated receptor	n/a
19	Q14994_TCL	Q14994	Nuclear receptor subfamily	inverse agonist
20	A1KVU8_TCL	A1KVU8	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
21	O75469_TCL	O75469	Nuclear receptor subfamily	n/a
22	P07202_TCL	P07202	Thyroid peroxidase (TPO)	weak inhibitor
23	Q7A6D8_TCL	Q7A6D8	deleted	n/a
24	Q9BJJ9_TCL	Q9BJJ9	Enoyl-ACP reductase	n/a
25	D5VCE0_TCL	D5VCE0	deleted	n/a
26	P54616_TCL	P54616	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a	IC50(nM) = 500.0
27	Q81JF8_TCL	Q81JF8	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
28	Q6LFB9_TCL	Q6LFB9	deleted	n/a
29	Q81GI3_TCL	Q81GI3	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a
30	P0AEK4_TCL	P0AEK4	Enoyl-[acyl-carrier-protein] reductase [NADH]	n/a	Ki(nM) = 0.007 IC50(nM) = 5.0