Ligand name: (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide
PDB ligand accession: 0WM
DrugBank: DB08916
PubChem: 10184653
ChEMBL: CHEMBL1173655
InChI Key: ULXXDDBFHOBEHA-CWDCEQMOSA-N
SMILES: CN(C)CC=CC(=O)Nc1cc2c(cc1OC3CCOC3)ncnc2Nc4ccc(c(c4)Cl)F

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Diazanaphthalenes
      • Subclass: Benzodiazines

List of proteins that are targets for DB08916

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P04626_0WM	P04626	inhibitor	IC50(nM) = 0.57 Kd(nM) = 5.0 EC50(nM) = 3.0
2	Q15303_0WM	Q15303	inhibitor	IC50(nM) = 1.0 Kd(nM) = 6.3
3	P00533_0WM	P00533	inhibitor	IC50(nM) = 0.01 Kd(nM) = 0.1 EC50(nM) = 7.5