Ligand name: Macitentan
PDB ligand accession: n/a
DrugBank: DB08932
InChI Key: JGCMEBMXRHSZKX-UHFFFAOYSA-N
SMILES: CCCNS(=O)(=O)Nc1c(c(ncn1)OCCOc2ncc(cn2)Br)c3ccc(cc3)Br

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Diazines
      • Subclass: Pyrimidines and pyrimidine derivatives

List of proteins that are targets for DB08932

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P25101_DB08932	P25101	Endothelin-1 receptor (Endothelin	antagonist	IC50(nM) = 0.5
2	P24530_DB08932	P24530	Endothelin receptor type	antagonist	IC50(nM) = 391.0