Ligand name: N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
PDB ligand accession: FFO
DrugBank: DB11596
PubChem: 149436;135398559;
ChEMBL: CHEMBL1908841
InChI Key: VVIAGPKUTFNRDU-STQMWFEESA-N
SMILES: c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCC2CNC3=C(N2C=O)C(=O)NC(=N3)N

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pteridines and derivatives
      • Subclass: Pterins and derivatives

List of proteins that are targets for DB11596

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	K4FZF8_FFO	K4FZF8	Serine hydroxymethyltransferase (EC	n/a
2	Q9AGP8_FFO	Q9AGP8	Dimethylglycine oxidase (DMGO)	n/a
3	Q5SLG6_FFO	Q5SLG6	Methylenetetrahydrofolate reductase (EC	n/a
4	A0A0R0IK90_FFO	A0A0R0IK90	Serine hydroxymethyltransferase (EC	n/a
5	P00477_FFO	P00477	Serine hydroxymethyltransferase (SHMT)	n/a
6	Q9WY54_FFO	Q9WY54	Aminomethyltransferase (EC 2.1.2.10)	n/a
7	Q7SIB6_FFO	Q7SIB6	Serine hydroxymethyltransferase (SHMT)	n/a
8	P0ABQ4_FFO	P0ABQ4	Dihydrofolate reductase (EC	n/a
9	Q9WYT0_FFO	Q9WYT0	Flavin-dependent thymidylate synthase	n/a
10	P0A825_FFO	P0A825	Serine hydroxymethyltransferase (SHMT)	n/a
11	Q834R3_FFO	Q834R3	Thymidylate synthase (TS)	n/a
12	P04818_FFO	P04818	Thymidylate synthase (TS)	n/a