Ligand name: TIVOZANIB
PDB ligand accession: AV9
DrugBank: DB11800
PubChem: 9911830
ChEMBL: CHEMBL1289494
InChI Key: SPMVMDHWKHCIDT-UHFFFAOYSA-N
SMILES: CC1=CC(=NC(=O)Nc2ccc(cc2Cl)Oc3ccnc4c3cc(c(c4)OC)OC)NO1

ClassyFire chemical classification:

List of proteins that are targets for DB11800

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q02763_AV9 Q02763 Angiopoietin-1 receptor (EC n/a
2 P17948_AV9 P17948 Vascular endothelial growth inhibitor
3 P16234_AV9 P16234 Platelet-derived growth factor inhibitor
4 P36888_AV9 P36888 Receptor-type tyrosine-protein kinase inhibitor
5 P35916_AV9 P35916 Vascular endothelial growth inhibitor
6 P35968_AV9 P35968 Vascular endothelial growth inhibitor
7 P09619_AV9 P09619 Platelet-derived growth factor inhibitor
8 P08581_AV9 P08581 Hepatocyte growth factor inhibitor
9 P10721_AV9 P10721 Mast/stem cell growth inhibitor
10 Q9H2G2_AV9 Q9H2G2 STE20-like serine/threonine-protein kinase n/a
11 P11362_AV9 P11362 Fibroblast growth factor inhibitor
12 Q13882_AV9 Q13882 Protein-tyrosine kinase 6 n/a